research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v1i4.2934 REL-A-013870 FEATURES OF THE DISTRIBUTION OF HLA- ANTIGENS AMONG PEOPLE OF THE UZBEK NATIONALITY IN THE SAMARKAND REGION ОСОБЕННОСТИ РАСПРЕДЕЛЕНИЯ HLA-АНТИГЕНОВ СРЕДИ ЛИЦ УЗБЕКСКОЙ НАЦИОНАЛЬНОСТИ В САМАРКАНДСКОЙ ОБЛАСТИ SAMARQAND VILOYATIDA O‘ZBEK MILLATIGA MANSUB SHAXSLAR ORASIDA HLA-ANTIGENLARNING TARQALISH XUSUSIYATLARI G.A. Dushanova Department of genetics and biotechnology, Samarkand State University, Department of Clinical and Laboratory Diagnostics with the Course of Clinical and Laboratory Diagnostics of the Faculty of Postgraduate Education, Department of Genetics and biotechnology, Samarkand State Medical University, Republic of Uzbekistan, Samarkand F.S. Nabiyeva Department of genetics and biotechnology, Samarkand State University, Department of Clinical and Laboratory Diagnostics with the Course of Clinical and Laboratory Diagnostics of the Faculty of Postgraduate Education, Department of Genetics and biotechnology, Samarkand State Medical University, Republic of Uzbekistan, Samarkand Fayzullayeva Kh. B. Department of genetics and biotechnology, Samarkand State University, Department of Clinical and Laboratory Diagnostics with the Course of Clinical and Laboratory Diagnostics of the Faculty of Postgraduate Education, Department of Genetics and biotechnology, Samarkand State Medical University, Republic of Uzbekistan, Samarkand N.A. Yunusova Department of genetics and biotechnology, Samarkand State University, Department of Clinical and Laboratory Diagnostics with the Course of Clinical and Laboratory Diagnostics of the Faculty of Postgraduate Education, Department of Genetics and biotechnology, Samarkand State Medical University, Republic of Uzbekistan, Samarkand 05 01 2023 2022 1 4 100 112 https://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.

The study of the HLA genetic profile of the population was carried out using the most complete set of modern HLA typing reagents. For the first time, the study of the HLA phenotype was carried out for a wide range of alleles of the A, B and DR loci, separately among the residents of the city and the village inhabiting the Samarkand region.

Изучение генетического профиля HLA населения проведено с использованием наиболее полного набора реагентов HLA-типирования. Впервые проведено изучение фенотипа HLA по широкому спектру аллелей локусов А, В и DR, отдельно среди жителей города и села Самаркандской области.

Aholining HLA genetik profilini o‘rganish zamonaviy HLA tiplash reagentlarining eng to‘liq to‘plamidan foydalangan holda o‘tkazildi. Ilk bor HLA fenotipini o‘rganish A, B va DR lokuslari allellarining keng doirasi bo‘yicha Samarqand viloyatida istiqomat qiluvchi shahar va qishloq aholisi orasida alohida-alohida o‘tkazildi.

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