research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v2i1.2858 REL-A-013794 OPTIMIZATION OF THE TREATMENT OF PATHOLOGICAL DRYNESS OF THE SKIN ОПТИМИЗАЦИЯ ЛЕЧЕНИЯ ПАТОЛОГИЧЕСКОЙ СУХОСТИ КОЖНЫХ ПОКРОВОВ TERINING PATOLOGIK QURUQLIGINI DAVOLASHNI OPTIMALLASHTIRISH F.B. Mirodilova Tashkent Medical Academy F.Kh. Abbaskhanova Tashkent Medical Academy J.M. Umarov Tashkent Medical Academy 05 02 2023 2023 2 1 241 245 https://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.

Xerosis (xerosis) of the skin - abnormal dryness of the skin, usually due to hyposecretion of the sebaceous glands (changes in the hydrolipid balance of the skin), which is the main cause of itching, and in some cases - infectious diseases of the skin. Skin xerosis is the main symptom of most dermatological diseases: it is present in patients with atopic dermatitis, psoriasis, seborrheic dermatitis, ichthyosis, follicular keratosis, irritant hand eczema, etc.

Ксероз (ксероз) кожи - аномальная сухость кожи, как правило, вследствие гипосекреции сальных желез (изменения гидролипидного баланса кожи), что является основной причиной зуда, а в ряде случаев - инфекционных заболеваний. кожи. Ксероз кожи является основным симптомом большинства дерматологических заболеваний: он присутствует у больных атопическим дерматитом, псориазом, себорейным дерматитом, ихтиозом, фолликулярным кератозом, раздражительной экземой рук и др.

Teri kserozi (kseroz) - terining anomal quruqligi bo‘lib, odatda yog‘ bezlarining giposekretsiyasi (terining gidrolipid muvozanatidagi o‘zgarishlar) tufayli yuzaga keladi va qichishishning asosiy sababi, ayrim hollarda esa terining yuqumli kasalliklari sababi hisoblanadi. Teri kserozi aksariyat dermatologik kasalliklarning asosiy simptomi hisoblanadi: u atopik dermatit, psoriaz, seboreyali dermatit, ixtioz, follikulyar keratoz, qo‘llarning iritant ekzemasi va boshqa kasalliklar bilan og‘rigan bemorlarda uchraydi.

 pathological dryness abnormal dryness hyposecretion dermatology atopic dermatitis psoriasis seborrheic dermatitis ichthyosis follicular keratosis irritant hand eczema патологическая сухость аномальная сухость гипосекреция дерматология атопический дерматит псориаз себорейный дерматит ихтиоз фолликулярный кератоз раздражающая экзема рук patologik quruqlik anomal quruqlik giposekretsiya dermatologiya atopik dermatit psoriaz seboreyali dermatit ixtioz follikulyar keratoz qo‘llarning iritant ekzemasi Alekhina S.P., Shcherbatyuk T.G. Ozone therapy: clinical and experimental aspects. - N.Novgorod 2003.-240 p. 101. Lomakina E. A. The role of the barrier function of the skin in the pathogenesis of some dermatoses // Modern problems of dermatovenereology, immunology and medical cosmetology. 2009, No. 2, pp. 87–90.1. Myadlets O. D., Adaskevich V. P. Morphofunctional dermatology. M.: Medlit, 2006. 752 p.4. Tkachenko S., Hernandez E. Aquaporins in the regulation of skin water balance // Cosmetics and medicine. 2011, No. 2, pp. 26–33. Ghadially R, Reed JT, Elias PM. Stratum corneum structure and function correlates with phenotype in psoriasis. J Invest Dermatol 1996; 107:558–64.4. 10.1111/1523-1747.ep12582813 Elias PM, Wood LC, Feingold KR. Epidermal pathogenesis of inflammatory. dermatoses. Am J Contact Dermatitis 1999; 10:119–26.5. 10.1097/01634989-199909000-00001 Scientific library of dissertations and abstracts disserCat http://www.dissercat.com/content/razrabotka-metoda-polucheniya-polinenasyshchennykh-zhirnykh-kislot#ixzz28AB8U65P) Linde YW. Dry skin in atopic dermatitis. Acta Derm Venereol: Suppl. (Stockh) 1992; 177:9–13.2. 10.2340/00015555177913 J. Pec, J. Dusek, Prakticke Lekarenstvi, 4, 86-89 (2008). M. Stuchlik, S. Zak, Patent CZ294004, (2001). Denda M, Sato J, Tsuchiya T et al. Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: implication for seasonal exacerbations of inflammatory dermatoses. J Invest Dermatol 1998; 111:873–8.3 10.1046/j.1523-1747.1998.00364.x Mendling W. Dermatovenerology Klinikum Frankfurt (Oder), AkademischesLehrkrankenhaus der Humboldt–Universitat (Charite) zu Berlin. Z ArztlFortbildQualitatssich 1998; 92 (3): 175–9. Elias PM, Wood LC, Feingold KR. Epidermal pathogenesis of inflammatory. dermatoses. Am J Contact Dermatitis 1999; 10:119–26.5. 10.1097/01634989-199909000-00001 Tkachenko S., Hernandez E. Dry skin in atopic dermatitis 2017, No. 2, pp. 16–33.