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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/refocus.v5i8.0813</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013568</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>16.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">Kataral-yiringli mastit bilan kasallangan sigirlar qonining biokimyoviy ko‘rsatkichlaridagi o‘zgarishlar</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>Changes in biochemical blood parameters in cows with catarrhal-purulent mastitis</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>Изменения биохимических показателей крови у коров, больных катарально-гнойным маститом</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <name>
            <surname>BOBOMURODOV</surname>
            <given-names>Rustam Ismoil o‘g‘li</given-names>
          </name>
          <aff>Veterinariya ilmiy-tadqiqot instituti, Samarqand, O‘zbekiston</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-09-05">
        <day>05</day>
        <month>09</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>8</issue>
      <fpage>77</fpage>
      <lpage>81</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013568/"/>
      <abstract xml:lang="uz">
        <p>Maqolada kataral-yiringli mastit bilan kasallangan sigirlar qonning ayrim biokimyoviy ko‘rsatkichlarida yuz beradigan o‘zgarishlar o‘rganilgan. Tadqiqotlar Samarqand viloyatining turli chorvachilik xo‘jaliklarida kataral-yiringli mastit bilan kasallangan sigirlarda olib borildi. Qon zardobidagi umumiy oqsil, glyukoza, aspartat aminotransferaza (AST) va laktatdegidrogenaza (LDH) miqdorlari kasallikning boshlanishida, 5- va 10-kunlarida aniqlandi. Tadqiqot natijalariga ko‘ra, kasallikning boshlang‘ich davrida umumiy oqsil, AST va LDH ko‘rsatkichlari yuqori bo‘lib, tajribaning 10-kuniga kelib ularning kamayishi kuzatildi. Glyukoza miqdorida esa sezilarli o‘zgarishlar aniqlanmadi. Olingan natijalar kataral-yiringli mastitda qonning biokimyoviy ko‘rsatkichlari kasallikning kechishi va organizmdagi yallig‘lanish jarayonlari dinamikasini baholashda qo‘shimcha diagnostik mezon sifatida foydalanish mumkinligini ko‘rsatdi.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>This article investigates changes in certain biochemical blood parameters in cows affected by catarrhal-purulent mastitis. The study was conducted on cows diagnosed with catarrhal-purulent mastitis in various livestock farms in the Samarkand Region. The levels of total protein, glucose, aspartate aminotransferase (AST), and lactate dehydrogenase (LDH) in blood serum were determined at the onset of the disease and on the 5th and 10th days. According to the results, the levels of total protein, AST, and LDH were elevated during the initial stage of the disease, while a decrease in these parameters was observed by the 10th day of the study. No significant changes in glucose levels were detected. The obtained results indicate that biochemical blood parameters in cows with catarrhal-purulent mastitis can be used as additional diagnostic criteria for assessing the course of the disease and the dynamics of inflammatory processes in the body.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>В статье изучены изменения некоторых биохимических показателей крови у коров, больных катарально-гнойным маститом. Исследования проводились на коровах с диагнозом «катарально-гнойный мастит» в различных животноводческих хозяйствах Самаркандской области. В сыворотке крови определяли содержание общего белка, глюкозы, аспартатаминотрансферазы (АСТ) и лактатдегидрогеназы (ЛДГ) в начале заболевания, а также на 5-е и 10-е сутки. Согласно результатам исследования, в начальный период заболевания показатели общего белка, АСТ и ЛДГ были повышены, а к 10-м суткам наблюдалось их снижение. При этом существенных изменений содержания глюкозы не выявлено. Полученные результаты свидетельствуют о том, что биохимические показатели крови при катарально-гнойном мастите могут использоваться в качестве дополнительных диагностических критериев для оценки течения заболевания и динамики воспалительных процессов в организме.</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>kataral-yiringli mastit</kwd>
        <kwd>sut bezining yallig‘lanishi</kwd>
        <kwd>qon</kwd>
        <kwd>qon zardobi</kwd>
        <kwd>umumiy oqsil</kwd>
        <kwd>glyukoza</kwd>
        <kwd>AST</kwd>
        <kwd>LDH</kwd>
        <kwd>biokimyoviy ko‘rsatkichlar</kwd>
        <kwd>yallig‘lanish</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>catarrhal-purulent mastitis</kwd>
        <kwd>mammary gland inflammation</kwd>
        <kwd>blood</kwd>
        <kwd>blood serum</kwd>
        <kwd>total protein</kwd>
        <kwd>glucose</kwd>
        <kwd>AST</kwd>
        <kwd>LDH</kwd>
        <kwd>biochemical parameters</kwd>
        <kwd>inflammation</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>катарально-гнойный мастит</kwd>
        <kwd>воспаление молочной железы</kwd>
        <kwd>кровь</kwd>
        <kwd>сыворотка крови</kwd>
        <kwd>общий белок</kwd>
        <kwd>глюкоза</kwd>
        <kwd>АСТ</kwd>
        <kwd>ЛДГ</kwd>
        <kwd>биохимические показатели</kwd>
        <kwd>воспаление</kwd>
      </kwd-group>
    </article-meta>
  </front>
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</article>
