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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/refocus.v5i7.0710</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013539</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>16.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">Comparative evaluation of the efficacy of different anthelmintic drugs against ovine dictyocaulosis</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>Сравнительная оценка эффективности различных антигельминтных препаратов при диктиокаулёзе овец</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>Qo‘ylar diktiokaulyoziga qarshi qo‘llanilgan turli antgelmint preparatlarining qiyosiy samaradorligi</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <name>
            <surname>SHARIPOVA</surname>
            <given-names>Laylo Sh.</given-names>
          </name>
          <aff>Scientific-Research Institute of Veterinary, Uzbekistan</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>YULDASHEV</surname>
            <given-names>Nurbek E.</given-names>
          </name>
          <aff>Tashkent Branch of Samarkand State University of Veterinary Medicine, Animal Husbandry and Biotechnology, Uzbekistan</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-08-05">
        <day>05</day>
        <month>08</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>7</issue>
      <fpage>57</fpage>
      <lpage>61</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013539/"/>
      <abstract xml:lang="en">
        <p>This article presents the results of a comparative evaluation of the therapeutic efficacy of different anthelmintic drugs used for the control of ovine dictyocaulosis. A review of the available literature indicates that dictyocaulosis is widely distributed worldwide, with the prevalence of infection ranging from 18.7 to 75.5 per cent. Previous studies conducted in the Republic of Uzbekistan reported that the extent of invasion reached up to 65.5 per cent in certain regions. However, the current epizootic status of ovine dictyocaulosis, its distribution across different regions of the country, as well as the efficacy of commonly used anthelmintic drugs and the level of parasite resistance to them, remain insufficiently investigated. The present study comparatively evaluated the therapeutic efficacy of LEVAMISOLE 75 and RICAZOL®, manufactured by Nita-Farm LLC (Russian Federation), and IVERMEC 1 %, manufactured in the People‘s Republic of China. All of these drugs are officially registered in the Republic of Uzbekistan and are widely used in veterinary practice.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>В данной статье представлены результаты сравнительной оценки терапевтической эффективности различных антигельминтных препаратов, применяемых для борьбы с диктиокаулёзом овец. Анализ литературных данных свидетельствует о том, что диктиокаулёз широко распространён во многих странах мира, а уровень заражённости животных варьирует от 18,7 до 75,5 %. Согласно ранее проведённым исследованиям в Республике Узбекистан, экстенсивность инвазии в отдельных регионах достигала 65,5 %. Вместе с тем современное эпизоотическое состояние диктиокаулёза, особенности его распространения в различных регионах республики, а также эффективность применяемых антигельминтных препаратов и уровень резистентности паразитов к ним изучены недостаточно. В ходе исследований была проведена сравнительная оценка терапевтической эффективности препаратов ЛЕВАМИЗОЛ 75 и РИКАЗОЛ®, производимых ООО «Нита-Фарм» (Российская Федерация), а также препарата IVERMEC 1 %, произведённого в Китайской Народной Республике.</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>Mazkur maqolada qo‘ylar diktiokaulyoziga qarshi kurashishda qo‘llanilayotgan turli antgelmint preparatlarining qiyosiy terapevtik samaradorligini baholash natijalari keltirilgan. Adabiyotlar tahliliga ko‘ra, diktiokaulyoz dunyoning ko‘plab mamlakatlarida keng tarqalgan bo‘lib, kasallikning uchrash darajasi 18,7–75,5 % ni tashkil etadi. O‘zbekiston Respublikasida o‘tkazilgan avvalgi tadqiqotlarda kasallikning ekstensivligi ayrim hududlarda 65,5 % gacha yetishi qayd etilgan. Shunga qaramay, hozirgi davrda respublikaning turli hududlarida diktiokaulyozning zamonaviy epizootik holati, tarqalish xususiyatlari, shuningdek amaliyotda qo‘llanilayotgan antgelmint preparatlarining samaradorligi va ularga nisbatan parazitlarning rezistentlik darajasi yetarli darajada o‘rganilmagan. Tadqiqot davomida O‘zbekiston Respublikasida davlat ro‘yxatidan o‘tgan hamda chorva hayvonlari gelmintozlariga qarshi veterinariya amaliyotida keng qo‘llanilayotgan Rossiya Federatsiyasining «Nita-Farm» MChJ tomonidan ishlab chiqarilgan LEVAMIZOL 75 va RIKAZOL®, shuningdek Xitoyda ishlab chiqarilgan IVERMEC 1 % antgelmint preparatlarining qiyosiy terapevtik samaradorligi o‘rganildi va olingan natijalar tahlil qilindi.</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>sheep</kwd>
        <kwd>helminth</kwd>
        <kwd>helminthiasis</kwd>
        <kwd>dictyocaulosis</kwd>
        <kwd>larva</kwd>
        <kwd>geohelminth</kwd>
        <kwd>Dictyocaulus filaria</kwd>
        <kwd>prevalence of infection</kwd>
        <kwd>intensity of infection</kwd>
        <kwd>deworming</kwd>
        <kwd>LEVAMISOLE 75</kwd>
        <kwd>RICAZOL®</kwd>
        <kwd>IVERMEC 1 %</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>овцы</kwd>
        <kwd>гельминт</kwd>
        <kwd>гельминтоз</kwd>
        <kwd>диктиокаулёз</kwd>
        <kwd>личинка</kwd>
        <kwd>геогельминт</kwd>
        <kwd>Dictyocaulus filaria</kwd>
        <kwd>экстенсивность инвазии</kwd>
        <kwd>интенсивность инвазии</kwd>
        <kwd>дегельминтизация</kwd>
        <kwd>ЛЕВАМИЗОЛ 75</kwd>
        <kwd>РИКАЗОЛ®</kwd>
        <kwd>IVERMEC 1 %</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>qo‘ylar</kwd>
        <kwd>gelmint</kwd>
        <kwd>gelmintoz</kwd>
        <kwd>diktiokaulyoz</kwd>
        <kwd>lichinka</kwd>
        <kwd>geogelmint</kwd>
        <kwd>Dictyocaulus filaria</kwd>
        <kwd>invaziya ekstensivligi</kwd>
        <kwd>invaziya intensivligi</kwd>
        <kwd>degelmintizatsiya</kwd>
        <kwd>LEVAMIZOL 75</kwd>
        <kwd>RIKAZOL®</kwd>
        <kwd>IVERMEC 1 %</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
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</article>
