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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v5i4.2331</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013458</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>16.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">QO‘YLAR XLAMIDIOZINI IMMUNOLOGIK TAHLILI HAMDA ABORT BO‘LGAN HOMILA TO‘QIMASIDAGI PATOMORFOLOGIK O‘ZGARISHLAR</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>IMMUNOLOGICAL ANALYSIS OF OVINE CHLAMYDIOSIS AND PATHOMORPHOLOGICAL CHANGES IN THE TISSUES OF ABORTED FETUSES</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>ИММУНОЛОГИЧЕСКИЙ АНАЛИЗ ХЛАМИДИОЗА ОВЕЦ И ПАТОМОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ В ТКАНЯХ АБОРТИРОВАННОГО ПЛОДА</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <name>
            <surname>N.I</surname>
            <given-names>Navruzov</given-names>
          </name>
          <aff>v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; kichik ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>N.Sh</surname>
            <given-names>Hamroqulov</given-names>
          </name>
          <aff>v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; kichik ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>U.B</surname>
            <given-names>Aktamov</given-names>
          </name>
          <aff>v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; v.f.f.d., katta ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti; kichik ilmiy xodim, Veterinariya ilmiy-tadqiqot instituti</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-05-05">
        <day>05</day>
        <month>05</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>4</issue>
      <fpage>230</fpage>
      <lpage>242</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013458/"/>
      <abstract xml:lang="uz">
        <p>Maqolada tug‘ishiga qisqa muddat qolgan va abort qilgan qo‘ylarning qon zardobida xlamidioz kasalligida (Chlamydia abortus ovis) immunologik tahlil natijalarini optik zichlik ko‘rsatkichlari o‘rganilgan. Chlamydia abortus ovisning qo‘ylar organizmida surunkali va o‘tkir shaklda kechishini IgG va IgM turlarini Qozog‘iston Davlatining “MVA GROUP” qo‘shma korxonasining test to‘plamida tekshirilgan natijalari va ularga matematik ishlov berilgan ko‘rsatkichlar keltirilgan. Tadqiqotlarni bajarish uchun Jizzax viloyatining G‘allaorol tumani “Rohat” fermer xo‘jaligi shuningdek mazkur tuman aholisining shaxsiy qo‘ylarida hamda Qashqadaryo viloyati Muborak tumani “Turon” Qoraqo‘lchilik MChJlarida tug‘ish davridan 12-14 kun avval abort qilgan va chala rivojlangan homilalarni immunologik, serologik hamda patomorfologik tahlillarning natijalari keltirilgan. Shuningdek Chlamydia abortus ovisdan nobud bo‘lgan 140-150 kunlik homilalarni ichki a‘zolarida patologoanatomik hamda gistologik o‘zgarishlari haqida ma‘lumotlar berilgan.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>The article presents the results of a study on optical density indicators obtained during the immunological analysis of blood serum from sheep in late pregnancy that experienced abortion due to chlamydiosis (Chlamydia abortus ovis). The study provides data on the determination of immunoglobulin classes IgG and IgM in both acute and chronic forms of Chlamydia abortus ovis infection in sheep, using diagnostic test kits produced by the joint venture “MVA GROUP” of the Republic of Kazakhstan, along with their statistical (mathematical) processing. The investigations were conducted on sheep from the “Rohat” farm in the Gallaaral district of the Jizzakh region, as well as on animals kept in private households within the same district, and in the “Turon” LLC (Karakul breeding farm) located in the Mubarek district of the Kashkadarya region. The study presents the results of immunological, serological, and pathomorphological analyses of sheep that aborted 12–14 days prior to lambing, as well as data on underdeveloped fetuses. In addition, information is provided on the pathoanatomical and histological changes observed in the internal organs of fetuses (140–150 days of gestation) that died as a result of infection with Chlamydia abortus ovis.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>В статье представлены результаты исследования оптической плотности при иммунологическом анализе сыворотки крови овец, находящихся на поздних сроках беременности и подвергшихся аборту, при хламидиозе (Chlamydia abortus ovis). Приведены результаты определения иммуноглобулинов классов IgG и IgM при остром и хроническом течении Chlamydia abortus ovis в организме овец с использованием тест-наборов совместного предприятия «MVA GROUP» Республики Казахстан, а также их статистическая (математическая) обработка. Исследования проводились на овцах фермерского хозяйства «Rohat» Галляаральского района Джизакской области, а также на животных, содержащихся в личных хозяйствах населения данного района, и в ООО «Turon» (каракулеводческое хозяйство) Мубарекского района Кашкадарьинской области. В работе представлены результаты иммунологических, серологических и патоморфологических исследований абортировавших овец за 12–14 дней до окота, а также данные по недоразвитым плодам. Кроме того, приведены сведения о патологоанатомических и гистологических изменениях во внутренних органах плодов (возраст 140–150 дней) павших вследствие инфицирования Chlamydia abortus ovis.</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>xlamidioz</kwd>
        <kwd>abort</kwd>
        <kwd>homila</kwd>
        <kwd>Chlamydia abortus ovis</kwd>
        <kwd>optik zichlik</kwd>
        <kwd>salbiy natija</kwd>
        <kwd>IgG-immunoglobulin</kwd>
        <kwd>C-reaktiv oqsil</kwd>
        <kwd>antigen</kwd>
        <kwd>immun tizim</kwd>
        <kwd>ijobiy natija</kwd>
        <kwd>substrat oqsil parafin</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>Chlamydiosis</kwd>
        <kwd>abortion</kwd>
        <kwd>fetus</kwd>
        <kwd>Chlamydia abortus ovis</kwd>
        <kwd>optical density negative result</kwd>
        <kwd>IgG immunoglobulin</kwd>
        <kwd>C-reactive protein</kwd>
        <kwd>antigen</kwd>
        <kwd>immune system</kwd>
        <kwd>positive result protein substrate</kwd>
        <kwd>parafin</kwd>
        <kwd>glycerin</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>Хламидиоз</kwd>
        <kwd>аборт</kwd>
        <kwd>плод</kwd>
        <kwd>Chlamydia abortus ovis</kwd>
        <kwd>оптическая плотность</kwd>
        <kwd>отрицательный результат</kwd>
        <kwd>иммуноглобулин IgG</kwd>
        <kwd>С-реактивный белок</kwd>
        <kwd>антиген иммунная система</kwd>
        <kwd>положительный результат</kwd>
        <kwd>белковый субстрат</kwd>
        <kwd>парафин</kwd>
      </kwd-group>
    </article-meta>
  </front>
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</article>
