research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v5i4.2295 REL-A-013422 02.00.00 FLAVONOID PROFILE OF “AS-INFUSUM” AND ITS BIOLOGICAL ACTIVITY ФЛАВОНОИДНЫЙ ПРОФИЛЬ «AS-INFUSUM» И ЕГО БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ “AS-INFUSUM”NING FLAVONOID PROFILI VA UNING BIOLOGIK FAOLLIGI Askarov Ibrokhim Rakhimjonovich Andijan State University; University of Business and Science; University of Business and Science Abdullaev Shavkat Vokhidovich Andijan State University; University of Business and Science; University of Business and Science Khaydarov Eldorbek Rakhimjon o‘g‘li Andijan State University; University of Business and Science; University of Business and Science Xasanbayevich Qirg‘izbayev Xusniddin Andijan State University; University of Business and Science; University of Business and Science 05 05 2026 2026 5 4 10 14 https://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.

This study investigates the flavonoid composition of the “As-Infusum” plant-based infusion using high-performance liquid chromatography (HPLC). The results demonstrated that rutin (39.12 mg/g) is the predominant component, determining the antioxidant and cardioprotective properties of the infusion. Additionally, flavonoids such as dihydroquercetin rosavin, quercetin, and salidroside were identified, contributing to the biological activity and enhancing the pharmacological and nutraceutical potential of the infusion.

В данной работе исследован флавоноидный состав настоя «As-Infusum» методом высокоэффективной жидкостной хроматографии (ВЭЖХ). Установлено, что рутин (39,12 мг/г) является основным компонентом, определяющим антиоксидантные и кардиопротекторные свойства настоя. Также выявлены флавоноиды, такие как дигидрокверцетин, розавин, кверцетин и салидрозид, способствующие повышению биологической активности и усиливающие фармакологический и нутрицевтический потенциал настоя.

Ushbu maqolada “As-Infusum” o‘simlik damlamasi tarkibidagi flavonoidlar yuqori samarali suyuqlik xromatografiyasi (HPLC) usuli yordamida tahlil qilindi. Tadqiqot natijalariga ko‘ra, rutin (39,12 mg/g) asosiy komponent sifatida aniqlanib, damlamaning antioksidant va kardioprotektiv xususiyatlarini belgilashi ilmiy asoslandi. Shuningdek dihidrokversetin, rozavin, kversetin va salidrozid kabi flavonoidlar aniqlanib, damlamaning biologik faolligi hamda farmakologik va nutrasevtik salohiyatini oshirishi ko‘rsatildi.

 As-Infusum flavonoids HPLC rutin antioxidant activity nutraceutical potential As-Infusum флавоноиды ВЭЖХ рутин антиоксидантная активность нутрицевтический потенциал As-Infusum flavonoidlar HPLC rutin antioksidant faollik nutrasevtik salohiyat Mamatqulova, S., & Asqarov, I. (2024). Study of the flavonoid composition of a biologically active supplement prepared from dill and coriander. Scientific Journal of Fergana State University, 30(3), 137-145. Harborne, J.B. (1994). The Flavonoids: Advances in Research Since 1980. Chapman & Hall. Middleton, E., Kandaswami, C., & Theoharides, T.C. (2000). The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacological Reviews. Pietta, P. (2000). Flavonoids as antioxidants. Journal of Natural Products. Materials of the Institute of Biology, Academy of Sciences of the Republic of Uzbekistan (2021-2023).