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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v5i5.2277</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013407</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>16.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">PAST PATOGENLI PARRANDA GRIPPI KASALLIGIGA QARSHI EMLANGAN JO‘JALAR ORGANIZMIGA INNOPROVET PROBIOTIGINING TA‘SIRI</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>EFFECT OF INNOPROVET PROBIOTIC ON THE ORGANISM OF CHICKENS VACCINATED AGAINST LOW-PATHOGENIC AVIAN INFLUENZA</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>ВЛИЯНИЕ ПРОБИОТИКА ИННОПРОВЕТ НА ОРГАНИЗМ ЦЫПЛЯТ, ВАКЦИНИРОВАННЫХ ПРОТИВ НИЗКОПАТОГЕННОГО ПТИЧЬЕГО ГРИППА</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <name>
            <surname>Nazarovich</surname>
            <given-names>Axmedov Baxodir</given-names>
          </name>
          <aff>Research Focus International Scientific Journal</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Uktamovich</surname>
            <given-names>Murodov Xurshid</given-names>
          </name>
          <aff>Research Focus International Scientific Journal</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>o‘g‘li</surname>
            <given-names>Sherqulov A‘zam Mirzoqul</given-names>
          </name>
          <aff>Research Focus International Scientific Journal</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-06-05">
        <day>05</day>
        <month>06</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>5</issue>
      <fpage>216</fpage>
      <lpage>224</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013407/"/>
      <abstract xml:lang="uz">
        <p>Maqolada sanoatlashgan parrandachilikda va fermer xo‘jaliklarida boqilayotgan Loman Braun zot jo‘jalariga Gallimune H9+ND past patogenli parranda grippi vaksinasi bilan emlash va Innoprovet probiotigini qo‘llash orqali parranda grippi kasalligiga qarshi samarali immunoprofilaktika jarayonini o‘rganish bo‘yicha ma‘lumotlar berilgan. Emlash va Innoprovet qo‘llanilgandan so‘ng 7 va 14-kunlarda barcha jo‘jalardan qon namunalari olindi hamda GATR (gemagglutinatsiyani tormozlash reaksiyasi) tahlili yordamida ularning immunitet holati baholandi. Tajriba guruhlaridagi parrandalarda nazorat guruhiga nisbatan antigemagglutinin (antitana) titrlari sezilarli darajada oshganligi aniqlandi. Tadqiqotlarning 14-kunida antitana titrlarining barqaror va yuqori darajada saqlanishi jo‘jalarda kuchli va uzoq davom etuvchi immunitet shakllanayotganligini namoyon qildi. Shuningdek, tajriba guruhidagi jo‘jalarda tirik vazn ortishi nazorat guruhiga nisbatan barqaror yuqori bo‘lganligi aniqlandi.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>The article provides information on the study of effective immunoprophylaxis against avian influenza disease through vaccination with the low-pathogenic avian influenza vaccine Gallimune H9+ND in Loman Brown chickens raised in industrial poultry farms and private farms, together with the use of the Innoprovet probiotic. After vaccination and application of Innoprovet, blood samples were taken from all chickens on days 7 and 14, and their immune status was assessed using the HI test (hemagglutination inhibition reaction). In the experimental groups, a significant increase in antihemagglutinin (antibody) titers was found compared to the control group. Stable and high maintenance of antibody titers on the 14th day of the study showed that chickens developed strong and long-lasting immunity. It was also found that live weight gain in the experimental group was consistently higher than in the control group.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>В статье представлены сведения об изучении процесса эффективной иммунопрофилактики против болезни птичьего гриппа путем вакцинации цыплят породы Ломан Браун, выращиваемых в промышленном птицеводстве и фермерских хозяйствах, низкопатогенной вакциной против птичьего гриппа Gallimune H9+ND и применения пробиотика Innoprovet. После вакцинации и применения Innoprovet на 7-й и 14-й дни у всех цыплят были взяты образцы крови, а состояние их иммунитета оценено с помощью анализа РТГА (реакции торможения гемагглютинации). У птиц опытных групп выявлено значительное повышение титров антигемагглютининов (антител) по сравнению с контрольной группой. Стабильное и высокое сохранение титров антител на 14-й день исследований показало формирование у цыплят сильного и продолжительного иммунитета. Также установлено, что прирост живой массы у цыплят опытной группы был стабильно выше, чем у контрольной группы.</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>jo‘jalar</kwd>
        <kwd>parranda grippi kasalligi</kwd>
        <kwd>Gallimune H9+ND past patogenli parranda grippi vaksinasi</kwd>
        <kwd>Innoprovet</kwd>
        <kwd>probiotik</kwd>
        <kwd>immunitet</kwd>
        <kwd>immunoprofilaktika</kwd>
        <kwd>antigen antitana</kwd>
        <kwd>antigemagglutinin</kwd>
        <kwd>serologiya</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>chicks</kwd>
        <kwd>avian influenza disease</kwd>
        <kwd>Gallimune H9+ND low-pathogenic avian influenza vaccine</kwd>
        <kwd>Innoprovet</kwd>
        <kwd>probiotic</kwd>
        <kwd>immunity</kwd>
        <kwd>immunoprophylaxis</kwd>
        <kwd>antigen</kwd>
        <kwd>antibody antihemagglutinin</kwd>
        <kwd>serology</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>цыплята</kwd>
        <kwd>болезнь птичьего гриппа</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
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</article>
