<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD with MathML3 v1.3 20210610//EN" "JATS-journalpublishing1-3-mathml3.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v5i5.2274</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013404</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">RESPIRATORY TRACT BURN AS A FACTOR IN THE SEVERITY OF BURN DISEASE: DIAGNOSIS, PATHOGENESIS AND CLINICAL COURSE</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>ОЖОГ ДЫХАТЕЛЬНЫХ ПУТЕЙ КАК ФАКТОР ТЯЖЕСТИ ОЖОГОВОЙ БОЛЕЗНИ: ДИАГНОСТИКА, ПАТОГЕНЕЗ И КЛИНИЧЕСКОЕ ТЕЧЕНИЕ</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>NAFAS YO‘LLARI KUYISHI KUYISH KASALLIGINING OG‘IRLIK OMILI SIFATIDA: TASHXIS, PATOGENEZ VA KLINIK KECHISH</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <name>
            <surname>A.U</surname>
            <given-names>Ziyodullaev</given-names>
          </name>
          <aff>Samarkand State Medical University and Termez Branch of Tashkent State Medical University</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>I.B</surname>
            <given-names>Mustafakulov</given-names>
          </name>
          <aff>Samarkand State Medical University and Termez Branch of Tashkent State Medical University</aff>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Z.A</surname>
            <given-names>Juraeva</given-names>
          </name>
          <aff>Samarkand State Medical University and Termez Branch of Tashkent State Medical University</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-06-05">
        <day>05</day>
        <month>06</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>5</issue>
      <fpage>201</fpage>
      <lpage>205</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013404/"/>
      <abstract xml:lang="en">
        <p>Respiratory tract burns are one of the most significant factors determining the severity and outcome of burn disease. This study presents an analysis of clinical, functional, and morphological changes in the respiratory system in 144 patients with respiratory tract damage secondary to burn injury. The pathogenesis, clinical course, and diagnostic capabilities of modern research methods are examined. Respiratory tract damage is associated with significant ventilation and gas exchange impairment, a high risk of infectious complications, and a significant increase in mortality. Comprehensive diagnostics using endoscopic and cytological methods enable timely detection of the extent of damage and prognosis of the disease.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>В статье анализируются ожоги дыхательных путей как один из наиболее значимых факторов, определяющих тяжесть и исход ожоговой болезни. Представлен анализ клинических, функциональных и морфологических изменений дыхательной системы у 144 пациентов с поражением дыхательных путей на фоне ожоговой травмы. Рассмотрены патогенез, клиническое течение и диагностические возможности современных методов исследования. Поражение дыхательных путей связано с выраженными нарушениями вентиляции и газообмена, высоким риском инфекционных осложнений и значительным повышением летальности. Комплексная диагностика с использованием эндоскопических и цитологических методов позволяет своевременно определить степень повреждения и прогнозировать течение заболевания.</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>Ushbu maqolada kuyish kasalligining og‘irligi va natijasini belgilovchi eng muhim omillardan biri sifatida nafas yo‘llari kuyishi tahlil qilinadi. Tadqiqotda kuyish jarohati fonida nafas yo‘llari shikastlangan 144 nafar bemorda nafas olish tizimidagi klinik, funksional va morfologik o‘zgarishlar ko‘rib chiqilgan. Nafas yo‘llari kuyishining patogenezi, klinik kechishi va zamonaviy tekshirish usullarining diagnostik imkoniyatlari yoritilgan. Nafas yo‘llarining shikastlanishi ventilyatsiya va gaz almashinuvining sezilarli buzilishi, infeksion asoratlar xavfining yuqoriligi hamda o‘lim ko‘rsatkichining ortishi bilan bog‘liqligi aniqlangan. Endoskopik va sitologik usullarni o‘z ichiga olgan kompleks diagnostika shikastlanish darajasini o‘z vaqtida aniqlash va kasallik kechishini prognoz qilish imkonini beradi.</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>respiratory tract burn</kwd>
        <kwd>burn disease</kwd>
        <kwd>diagnostics</kwd>
        <kwd>bronchoscopy</kwd>
        <kwd>pathogenesis</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>ожог дыхательных путей</kwd>
        <kwd>ожоговая болезнь</kwd>
        <kwd>диагностика бронхоскопия</kwd>
        <kwd>патогенез</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>nafas yo‘llari kuyishi</kwd>
        <kwd>kuyish kasalligi</kwd>
        <kwd>diagnostika</kwd>
        <kwd>bronxoskopiya patogenez</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <ref id="r1">
        <label>1</label>
        <mixed-citation>Alekseev A.A., Ushakova T.A., Krutikov M.G., et al. Sepsis as a failure of the body&apos;s adaptive responses to a burn wound. / In the book: Current issues of thermal injury. St. Petersburg, 2002. pp. 114-116.</mixed-citation>
      </ref>
      <ref id="r2">
        <label>2</label>
        <mixed-citation>Alekseev A.A. Modern methods of treatment of burns and burn disease // Combustiology, 2004. - №2. – p. 1-11.</mixed-citation>
      </ref>
      <ref id="r3">
        <label>3</label>
        <mixed-citation>Akhmedov M.G., Aliyev M.A., Tagirov S.A. Combined electrothermal injury, mutual aggravation syndrome. // International Congress &apos;&apos;Combustiology at the Turn of the Century&apos;&apos;. Moscow, 2000. – p.41-42.</mixed-citation>
      </ref>
      <ref id="r4">
        <label>4</label>
        <mixed-citation>Bagnenko S.F., Krylov K.M., Kozulin D.A., et al. Department of Thermal Injuries (Years, Problems). In the book: Current Issues of Thermal Injury. St. Petersburg, 2002. pp. 34-36.</mixed-citation>
      </ref>
      <ref id="r5">
        <label>5</label>
        <mixed-citation>Bagnenko S.F., Krylov K.M., Ershova I.N. On the 60th Anniversary of the Burn Center of the I.I. Dzhanelidze Research Institute of Emergency Care. // Emergency Medical Care. Proc. of the Int. Conf. &quot;Actual Problems of Thermal Trauma&quot; dedicated to the 60th Anniversary of the Burn Center of the I.I. Dzhanelidze Research Institute of Emergency Care. St. Petersburg (June 20–22), 2006.– No. 3. – Vol. 7. – pp. 15–16.</mixed-citation>
      </ref>
      <ref id="r6">
        <label>6</label>
        <mixed-citation>Dmitriev Yu.K., Duganov V.K., Borzenkov S.A. et al. Bronchoscopy in the diagnosis and treatment of lung diseases // Military Medical Journal. - 1994, No. 10. - P.47-51.</mixed-citation>
      </ref>
      <ref id="r7">
        <label>7</label>
        <mixed-citation>Dmitriev D.M., Smolnikov V.V., Kryklya A.S. Evaluation of the effectiveness of early transportation of patients with severe thermal injury to a specialized center // Nizhny Novgorod Medical Journal, 2004. - Combustiology, supplement, pp. 36-37.</mixed-citation>
      </ref>
      <ref id="r8">
        <label>8</label>
        <mixed-citation>Zhegalov V.A. Polemical notes on the assessment of the severity of burns and burn shock // Conf. &apos;&apos;Actual problems of traumatology and orthopedics&apos;&apos;. Abstracts of reports. Nizhny Novgorod, 2001. - pp. 8-10.</mixed-citation>
      </ref>
      <ref id="r9">
        <label>9</label>
        <mixed-citation>Zilber A.P. Respiratory failure. - M.: Medicine, 1989. - 512 p.</mixed-citation>
      </ref>
      <ref id="r10">
        <label>10</label>
        <mixed-citation>Kurbanov Sh.I., Ustinova T.S., Alekseev A.A. Early bronchoscopic and morphological diagnostics with prognosis in case of thermal inhalation injury // Bull. experimental biology and medicine. - 1997. - V. 124, N 8. P.221-225.</mixed-citation>
      </ref>
      <ref id="r11">
        <label>11</label>
        <mixed-citation>Lavrov V.A., Vinogradov V.L. Burn shock: pathogenesis, clinical picture, treatment // Scientific and practical journal of the Vishnevsky Institute of Surgery, Russian Academy of Medical Sciences, 2000. - No. 2. – p. 1-5.</mixed-citation>
      </ref>
      <ref id="r12">
        <label>12</label>
        <mixed-citation>Nikitin E.A., Ismagilov I.V., Khunafin A.S. et al. Diagnostics and treatment of respiratory damage in thermal injury // Nizhny Novgorod Medical Journal, 2004. – Combustiology, supplement, p.93.</mixed-citation>
      </ref>
      <ref id="r13">
        <label>13</label>
        <mixed-citation>Onuprienko A.Yu., Dyachkova E.V., Alaeva V.V. et al. Organization of medical care for burn victims in Khabarovsk Krai // Nizhny Novgorod Medical Journal, 2004. - Combustiology, supplement, pp. 48-49.</mixed-citation>
      </ref>
      <ref id="r14">
        <label>14</label>
        <mixed-citation>Sukharev Yu.P., Raskostova S.V., Davydov P.V. Application of fiberoptic bronchoscopy in case of thermal inhalation damage of the respiratory tract // Proceedings of the memorial scientific-practical. conf. in memory of prof. R.I.Lifshitz &apos;&apos;Actual problems of combustiology, resuscitation and extreme medicine&apos;&apos;. - Chelyabinsk: ChMedA. 1996. - pp. 98-99.</mixed-citation>
      </ref>
      <ref id="r15">
        <label>15</label>
        <mixed-citation>Tarasenko M.Yu., Shpakov I.F., Petrachkov S.A. Severe thermal inhalation injury: treatment principles, problems. // Collection of scientific papers of the I Congress of Combustiologists of Russia “World without Burns”, Moscow (October 17–21), 2005. – pp. 208–209.</mixed-citation>
      </ref>
      <ref id="r16">
        <label>16</label>
        <mixed-citation>Khadzhibaev A.M., Fayazov A.D., Alimov R.A. et al. Ways to optimize the diagnosis and treatment of burn victims. // Collection of scientific papers of the 1st Congress of Combustiologists of Russia “World without Burns”, Moscow (October 17–21), 2005. – p. 33.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
