research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v5i2.2072 REL-A-013359 16.00.00 PARRANDALARDA EYMERIOZGA QARSHI VAKSINALAR VA ANTIKOKSIDIAL DORILARNING SAMARADORLIGI THE EFFECTIVENESS OF VACCINES AND ANTICOCCIDIAL DRUGS AGAINST EIMERIOSIS IN POULTRY ЭФФЕКТИВНОСТЬ ВАКЦИН И АНТИКОКЦИДНЫХ ПРЕПАРАТОВ ПРОТИВ ЭЙМЕРОЗА У ДОМАШНЕЙ ПТИЦЫ Avezimbetov Shavkat Do‘simbetovich Samarqand davlat veterinariya meditsinasi, chorvachilik va biotexnologiyalar universiteti Nukus filiali. Khojamuratova Azada Yakupbay qizi 05 03 2026 2026 5 2 268 273 https://creativecommons.org/licenses/by/4.0 Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.

Ushbu maqolada parrandachilik xo‘jaliklarida keng tarqalgan eymerioz (koksidioz) kasalligiga qarshi kurashning zamonaviy usullari, xususan vaksinalar va antikoksidial dorilarning samaradorligi, afzalliklari hamda cheklovlari batafsil tahlil qilingan. Tadqiqotda ionofor va kimyoviy antikoksidial preparatlarning ta‘sir mexanizmi, ulardan foydalanish strategiyalari, parazitlarda doriga chidamlilik (rezistentlik) shakllanishi va bu jarayonning global miqyosdagi oqibatlari ilmiy manbalar asosida yoritilgan.

This article provides a detailed analysis of the modern methods of combating eimeriosis (coccidiosis), a disease widespread on poultry farms, in particular of the effectiveness, the advantages and the limitations of vaccines and anticoccidial drugs. On the basis of scientific sources, the study covers the mechanism of action of ionophore and chemical anticoccidial preparations, the strategies of their use, the formation of drug resistance in parasites and the global-scale consequences of this process.

В данной статье представлен подробный анализ современных методов борьбы с кокцидиозом, широко распространенным заболеванием на птицефермах, в частности, эффективности, преимуществ и ограничений вакцин и противококцидийных препаратов. Исследование охватывает механизм действия ионофорных и химических противококцидийных препаратов, стратегии их применения, развитие лекарственной устойчивости у паразитов и глобальные последствия этого процесса на основе научных источников.

 eymerioz koksidioz Eimeria antikoksidial dorilar ionoforlar kimyoviy koksidiostatiklar vaksina jonli zaiflashtirilgan vaksinalar subunit vaksina DNK vaksina bioxavfsizlik probiotiklar o‘simlik ekstraktlari rezistentlik parrandachilik eimeriosis coccidiosis Eimeria anticoccidial drugs ionophores chemical coccidiostats vaccine live attenuated vaccines subunit vaccine DNA vaccine biosecurity probiotics plant extracts resistance poultry farming эймерия кокцидиоз Eimeria противококцидийные препараты ионофоры химические кокцидиостатики вакцина живые аттенуированные вакцины субъединичная вакцина ДНК-вакцина биобезопасность пробиотики растительные экстракты резистентность птицеводство Avezimbetov, S., Madetova, M., Madetova, N., & Joldasbaeva, V. (2023). VETERINARIYADA GEMOTERAPIYA. ANEMIYALAR VA QON ZARDOBIDA TEMIRNI ANIQLASH, QON RETRAKSIYASINI ANIQLASH, 3(2), 509-516. Blake, D. P., & Tomley, F. M. (2014). RECENT ADVANCES IN UNDERSTANDING EIMERIA SPECIES AND THE DEVELOPMENT OF VACCINES. PARASITOLOGY, 141(11), 1403–1416. Davlatov, R. B., & Khushnazarov, A. K. (2024). Diagnosis and chemoprophylaxis of rabbit eymeriosis. In E3S Web of Conferences (Vol. 480, p. 03020). EDP Sciences. Jenkins, M. C. et al. (2019). EIMERIA VACCINES FOR POULTRY. POULTRY SCIENCE, 98(3), 886–899. Kamal K. et al. QORAQALPOG ‘ISTONDA PARRANDALAR EYMERIOZI KASALLIGINI TARQALISHI VA OLDINI OLISH //JOURNAL OF VETERINARY SCIENCE. – 2025. – Т. 8. – №. 10. – С. 1-6. Lee, S. H., Lillehoj, H. S., & Park, D. W. (2011). COCCIDIOSIS CONTROL: CURRENT STATUS AND FUTURE PROSPECTS. VETERINARY PARASITOLOGY, 181(1–2), 1–8. Maulenovich, A. K., & Rustam O‘g‘li, Y. A. (2025). QORAQALPOG ‘ISTONDA PARRANDALARDA UCHRAYDIGAN PARAZITAR KASALLIKLAR VA ULARGA QARSHI KURASH CHORALARI 2(4), 103-108. Mountzouris, K. C. et al. (2010). EFFECTS OF PROBIOTIC SUPPLEMENTATION ON BROILER PERFORMANCE, INTESTINAL MICROFLORA AND IMMUNITY. POULTRY SCIENCE, 89(1), 58–67. Noack, S., Chapman, H. D., & Selzer, P. M. (2019). ANTICOCCIDIAL DRUGS OF THE POULTRY INDUSTRY: RECENT PROGRESS AND FUTURE OUTLOOK. POULTRY SCIENCE, 98(9), 3791–3803. Shavkat, A., Karamaddinovich, B. K., & qizi Zaripboyeva, Z. S. (2025). INFESTATION OF SHEEP WITH INTESTINAL CESTODES IN UZBEKISTAN: EPIZOOTIOLOGICAL STUDIES, NEW PARASITIC SPECIES, AND ENVIRONMENTAL FACTORS. Modern digital technologies in education: problems and prospects, 2(2), 151-156. Shavkat, A., Karamaddinovich, B. K., & qizi Zaripboyeva, Z. S. (2025). INTESTINAL CESTODE INFESTATION IN SHEEP IN UZBEKISTAN: EPIZOOTIOLOGICAL STUDIES, ECOLOGICAL FACTORS, AND SEASONAL DYNAMICS. Prospects for innovative technologies in science and education, 2(2), 190-196. Shavkat, A., Karamaddinovich, B. K., & qizi Khojamuratova, A. Y. (2025). INFECTION OF SHEEP WITH INTESTINAL CESTODES IN UZBEKISTAN: EPIZOOTIOLOGICAL ANALYSIS, ECOLOGICAL FACTORS, AND PREVENTIVE MEASURES. The latest news and research in education, 2(2), 69-77. Shavkat A., Karamaddinovich B. K. qizi Khojamuratova, AY (2025) //INFECTION OF SHEEP WITH INTESTINAL CESTODES IN UZBEKISTAN: EPIZOOTIOLOGICAL ANALYSIS, ECOLOGICAL FACTORS, AND PREVENTIVE MEASURES. The latest news and research in education. – Т. 2. – №. 2. – С. 69-77. Shavkat A. et al. JO ‘JALAR EYMERIOZI: ETIOLOGIYASI, KLINIK BELGILAR VA OLDINI OLISH CHORALAR. – 2025. Williams, R. B. (2002). ANTICOCCIDIAL VACCINES FOR BROILER CHICKENS: PATHWAYS TO SUCCESS. AVIAN PATHOLOGY, 31(4), 317–353.