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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v5i2.2065</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013352</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">“OPEN ABDOMEN” TACTICS FOR DISSEMINATED PERITONITIS: INDICATIONS, COMPLICATIONS, AND TREATMENT RESULTS</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>ТАКТИКА «ОТКРЫТОГО ЖИВОТА» ПРИ РАСПРОСТРАНЁННОМ ПЕРИТОНИТЕ: ПОКАЗАНИЯ, ОСЛОЖНЕНИЯ И РЕЗУЛЬТАТЫ ЛЕЧЕНИЯ</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>TARQALGAN PERITONITDA “OCHIQ QORIN” TAKTIKASI: KO‘RSATMALAR, ASORATLAR VA DAVOLASH NATIJALARI</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Mustafakulov Ishnazar Boynazarovich</string-name>
          <aff>Samarkand State Medical University and Termez Branch of Tashkent State Medical University</aff>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Tokhirov Sheroz Mardonkulovich</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Djuraeva Zilola Aramovna</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Mustafakulov Ishnazar Boynazarovich</string-name>
          <aff>Samarkand State Medical University and Termez Branch of Tashkent State Medical University</aff>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Tokhirov Sheroz Mardonkulovich</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Djuraeva Zilola Aramovna</string-name>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-03-05">
        <day>05</day>
        <month>03</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2026</year>
      </pub-date>
      <volume>5</volume>
      <issue>2</issue>
      <fpage>226</fpage>
      <lpage>231</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013352/"/>
      <abstract xml:lang="en">
        <p>The open abdomen approach is used for the most severe forms of disseminated peritonitis, accompanied by abdominal sepsis and intra-abdominal hypertension syndrome. The aim of this study was to evaluate the indications, complication rates, and clinical efficacy of the open abdomen approach in patients with disseminated peritonitis. It was found that this approach is justified when the indications are strictly followed; however, it is associated with a high complication rate and requires an individualized approach and dynamic patient monitoring.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>Тактика «open abdomen» (открытый живот) применяется при наиболее тяжёлых формах распространённого перитонита, сопровождающихся абдоминальным сепсисом и синдромом внутрибрюшной гипертензии. Целью исследования явилась оценка показаний, частоты осложнений и клинической эффективности применения тактики open abdomen у больных с распространённым перитонитом. Установлено, что метод является обоснованным при строгом соблюдении показаний, однако сопровождается высокой частотой осложнений и требует индивидуализированного подхода и динамического мониторинга состояния пациента.</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>«Open abdomen» (ochiq qorin) taktikasi abdominal sepsis va qorin ichki gipertenziyasi sindromi bilan kechuvchi tarqalgan peritonitning eng og‘ir shakllarida qo‘llaniladi. Tadqiqotning maqsadi tarqalgan peritonit bilan og‘rigan bemorlarda «open abdomen» taktikasini qo‘llashga ko‘rsatmalar, asoratlar chastotasi va klinik samaradorligini baholashdan iborat bo‘ldi. Aniqlandiki, ushbu usul ko‘rsatmalarga qat‘iy rioya qilinganda asoslangan hisoblanadi, biroq u asoratlarning yuqori chastotasi bilan kuzatiladi hamda individual yondashuvni va bemor holatining dinamik monitoringini talab etadi. /</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>open abdomen</kwd>
        <kwd>laparostomy</kwd>
        <kwd>generalized peritonitis</kwd>
        <kwd>abdominal sepsis</kwd>
        <kwd>intra-abdominal hypertension</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>открытый живот</kwd>
        <kwd>лапаростомия</kwd>
        <kwd>распространённый перитонит</kwd>
        <kwd>абдоминальный сепсис</kwd>
        <kwd>внутрибрюшная гипертензия</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>open abdomen</kwd>
        <kwd>laparostomiya</kwd>
        <kwd>tarqalgan peritonit</kwd>
        <kwd>abdominal sepsis</kwd>
        <kwd>qorin ichki gipertenziyasi</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <ref id="r1">
        <label>1</label>
        <mixed-citation>Litvin A.A. Scale for early detection and prediction of outcomes of abdominal sepsis / A.A. Litvin, I.Z. Weisbein, L.V. Savich et al. // Proceedings of the All-Russian Surgical Forum - 2019 in collaboration withXXII Congress of the Russian Society of Endoscopic Surgery (ROEKh named after Academician V.D. Fedorov). – Moscow, 2019. – P.346–346.</mixed-citation>
      </ref>
      <ref id="r2">
        <label>2</label>
        <mixed-citation>Litvin, A. A. ScalePIPAS for early prediction of abdominal sepsis / A. A. Litvin, E. N. Kolokoltseva, E. A. Litvina // Collection of materials of the VII All-Russian scientific and practical conference with international participation &quot;Innovations in the health of the nation&quot;, St. Petersburg, November 7-8, 2019. - 2019. - P. 42-44.</mixed-citation>
      </ref>
      <ref id="r3">
        <label>3</label>
        <mixed-citation>Makarov I. V. Effectiveness of modern prognostic scales for assessing the severity of the condition of patients with acute severe pancreatitis. / I. V. Makarov, I. A. Mustafaev, A. V. Kurashev, L. A. Budorina, L. V. Gerasimov // Science and innovation in medicine. - 2020. - No. 5 (4) - P. 278-282.</mixed-citation>
      </ref>
      <ref id="r4">
        <label>4</label>
        <mixed-citation>Makarova, V. D. Comparative characteristics of urgent abdominal pathology complicated by purulent peritonitis in the period 2017-2019 using the example of the Kirov Regional State Budgetary Healthcare Institution “Kirov Emergency Hospital” / V. D. Makarova //Polish Journal of Science. – 2020. – No. 27. – P. 28-33.</mixed-citation>
      </ref>
      <ref id="r5">
        <label>5</label>
        <mixed-citation>Methodology for assessing the severity of widespread peritonitis and the likelihood of relaparotomy / B. V. Sigua, V. P. Zemlyanoy, S. V. Petrov [et al.] // Grekov Surgery Bulletin. - 2021. - Vol. 180, No. 2. - P. 21-27.</mixed-citation>
      </ref>
      <ref id="r6">
        <label>6</label>
        <mixed-citation>Mikhailichenko V.Yu. Clinical and diagnostic parallels of enteral insufficiency and endogenous intoxication in peritonitis / V.Yu. Mikhailichenko, S.A. Samarin, P.S. Trofimov // Medical Bulletin of the Ministry of Internal Affairs.2019:3(100):33-39.</mixed-citation>
      </ref>
      <ref id="r7">
        <label>7</label>
        <mixed-citation>Mikhailichenko V.Yu., Tatarczuk P.A., Kislyakov V.V., Reznicenko A.M., Butyrsky A.G., Kerimov E.Ya., Pilipchuk A.A., Samarin S.A. &quot;Application of the method of programmed sanitation of the abdominal cavity in diffuse purulent peritonitis: clinical observation and review&quot; Tavrichesky Medico-Biological Bulletin,vol. 25, no. 2, 2022, pp. 147-151.</mixed-citation>
      </ref>
      <ref id="r8">
        <label>8</label>
        <mixed-citation>Mikhailichenko, V.Yu. Clinical and diagnostic parallels of enteral insufficiency and endogenous intoxication in peritonitis / V.Yu. Mikhailichenko, S.A. Samarin, P.S. Trofimov // Medical Bulletin of the Ministry of Internal Affairs. - 2019. - T. S, No. 3. - P. 33-39.</mixed-citation>
      </ref>
      <ref id="r9">
        <label>9</label>
        <mixed-citation>Mikhelson, E.P. Diagnostic value of determining the level of procalcitonin in abdominal surgery / E.P. Mikhelson, S.A. Shlyapnikov, N.R. Nasser, I.M. Batyrshin, D.S. Sklizkov, Yu.S. Ostroumova, V.G. Dvoinov, M.A. Borodin // Journal MediaAl. – 2019. – T. 23, No. 1. – P. 25-</mixed-citation>
      </ref>
      <ref id="r10">
        <label>10</label>
        <mixed-citation>Mrugova, T.M. Seroresistance and antibiotic resistance of strainsEscherichia coli isolated from patients with infectious and inflammatory diseases / T. M. Mrugova, V. A. Gritsenko, V. A. Ageevets // Problems of Medical Mycology. - 2020. - Vol. 22, No. 3. - P. 108.</mixed-citation>
      </ref>
      <ref id="r11">
        <label>11</label>
        <mixed-citation>On the problems of treating widespread purulent peritonitis / A. M. Karsanov, S. S. Maskin, A. A. Khasieva [et al.] // Modern science: current problems of theory and practice. Series: Natural and technical sciences. - 2020. - No. 8. - P. 168-172.</mixed-citation>
      </ref>
      <ref id="r12">
        <label>12</label>
        <mixed-citation>Ostroumova Yu.S. Scale systems for predicting the course and outcome of peritonitis and abdominal sepsis / Yu.S. Ostroumova, I.M. Batyrshin, N.R. Nasser, D.S. Sklizkov, E.P. Ryazanova, M.A. Borodina, S.A. Shlyapnikov // Bulletin of the DSEA. – 2019. - No. 4 (33). - S64-71.</mixed-citation>
      </ref>
      <ref id="r13">
        <label>13</label>
        <mixed-citation>Plotkin D.V., Reshetnikov M.N., Sinitsyn M.V., Zyuzya Yu.R. Disseminated peritonitis and splenitis caused by MAC infection in a patient with immunosuppression. Journal of Infectology. 2021;13(3):135-142. https://doi.org/<pub-id pub-id-type="doi">10.22625/2072-6732-2021-13-3-135-142</pub-id></mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
