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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i12.1933</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013244</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">RADIOLOGICAL ASSESSMENT OF BONE REGENERATION DYNAMICS FOLLOWING ONE-STAGE DENTAL IMPLANTATION USING A‑PRF TECHNOLOGY</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>РЕНТГЕНОЛОГИЧЕСКАЯ ОЦЕНКА ДИНАМИКИ РЕГЕНЕРАЦИИ КОСТНОЙ ТКАНИ ПОСЛЕ ОДНОЭТАПНОЙ ДЕНТАЛЬНОЙ ИМПЛАНТАЦИИ С ИСПОЛЬЗОВАНИЕМ ТЕХНОЛОГИИ A-PRF</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>A-PRF TEXNOLOGIYASIDAN FOYDALANGAN HOLDA BIR BOSQICHLI STOMATOLOGIK IMPLANTATSIYADAN SO‘NG SUYAK REGENERATSIYASI DINAMIKASINI RENTGENOLOGIK BAHOLASH</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Nigora Pardaevna Mardonova</string-name>
          <aff>Department of Maxillofacial Surgery, Samarkand State Medical University, Samarkand, Uzbekistan</aff>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Jaloliddin Fazliddin o‘g‘li Nurmurodov</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Navruz Khabibullaevich Bobonazarov</string-name>
          <aff>Department of Pediatric Surgical Dentistry, Tashkent State Medical University, Tashkent, Uzbekistan</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-01-05">
        <day>05</day>
        <month>01</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>12</issue>
      <fpage>233</fpage>
      <lpage>239</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013244/"/>
      <abstract xml:lang="en">
        <p>Background: Immediate (one-stage) implant placement reduces total rehabilitation time but occurs during early post-extraction remodeling and may be associated with delayed healing. Advanced Platelet‑Rich Fibrin (A‑PRF) is an autologous fibrin matrix enriched with platelets and leukocytes and is used as a regenerative adjunct to stabilize the wound and deliver growth factors.</p>
        <p>Objective. To describe radiological healing dynamics 4 months after one-stage dental implantation performed with adjunctive A‑PRF.</p>
        <p>Methods. A pilot case series included 9 patients treated with immediate implant placement. Periapical radiographs were obtained at baseline and at 4 months and assessed for peri‑implant radiolucency, qualitative trabecular maturation, and signs of bone fill within the implant-socket gap. Early clinical follow-up documented soft‑tissue response and pain.</p>
        <p>Results. Follow-up radiographs demonstrated the absence of peri‑implant radiolucent zones and no radiographic signs of destructive bone resorption. Progressive trabecular consolidation and increased mineralization were observed in the surgical area. Postoperative edema and hyperemia were mild and pain complaints were limited.</p>
        <p>Conclusion. In this small pilot series, A‑PRF use during one-stage implantation was associated with favorable radiographic healing at 4 months. Controlled studies with standardized measurements (marginal bone levels, CBCT densitometry, ISQ) are recommended.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>Оценена рентгенологическая динамика через 4 месяца после одномоментной имплантации с применением A‑PRF. Не выявлено зон пери‑имплантной радиолюценции и признаков резорбции; отмечены восстановление трабекулярной структуры и консолидация костной ткани. Цель. Описать динамику рентгенологического заживления через 4 месяца после одноэтапной дентальной имплантации с применением адъювантного A-PRF. Методы. В пилотную серию случаев вошли 9 пациентов, которым была проведена немедленная имплантация. Периапикальные рентгенограммы были получены исходно и через 4 месяца и оценены на предмет периимплантатной рентгенопрозрачности, качественного созревания трабекул и признаков заполнения костной тканью промежутка между имплантатом и лункой. Раннее клиническое наблюдение зафиксировало реакцию мягких тканей и боль. Результаты. Рентгенограммы при последующем наблюдении показали отсутствие периимплантатных рентгенопрозрачных зон и рентгенологических признаков деструктивной резорбции кости. В области хирургического вмешательства наблюдалась прогрессирующая консолидация трабекул и повышенная минерализация. Послеоперационный отек и гиперемия были умеренными, а жалобы на боль были незначительными. Вывод. В этой небольшой пилотной серии использование A-PRF во время одноэтапной имплантации было связано с благоприятным рентгенологическим заживлением через 4 месяца. Рекомендуется проведение контролируемых исследований со стандартизированными измерениями (уровень краевой костной ткани, денситометрия с помощью КЛКТ, ISQ).</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>A‑PRF texnologiyasi qo‘llangan bir etapli dental implantatsiyadan so‘ng 4 oyda olingan rentgenologik ma‘lumotlar tahlil qilindi. Peri‑implant sohada radiolyutsent zonalar va resorbsiya belgilarining yo‘qligi, trabekulyar tuzilmaning tiklanishi hamda mineralizatsiya jarayonining faollashishi qayd etildi. Maqsad. Qo‘shimcha A‑PRF bilan bajarilgan bir bosqichli stomatologik implantatsiyadan 4 oy o‘tgach, radiologik shifo dinamikasini tavsiflash. Usullar. Sinov holatlari seriyasiga darhol implant qo‘yish bilan davolangan 9 bemor kiritilgan. Periapikal rentgenografiyalar boshlang‘ich bosqichda va 4 oydan keyin olingan va peri‑implant radiolucentligi, sifatli trabekulyar yetilish va implant-soket oralig‘ida suyak to‘lishi / belgilari baholangan. Erta klinik kuzatuv yumshoq to‘qimalarning javobi va og‘rig‘ini hujjatlashtirgan. Natijalar. Kuzatuv rentgenografiyalari peri‑implant radiolucent zonalarining yo‘qligini va suyakning destruktiv rezorbsiyasining rentgenologik belgilari yo‘qligini ko‘rsatdi. Jarrohlik sohasida progressiv trabekulyar konsolidatsiya va mineralizatsiyaning oshishi kuzatildi. Operatsiyadan keyingi shish va giperemiya yengil bo‘lgan va og‘riq shikoyatlari cheklangan. Xulosa. Ushbu kichik sinov seriyasida bir bosqichli implantatsiya paytida A‑PRF dan foydalanish 4 oydan keyin ijobiy rentgenologik shifo bilan bog‘liq edi. Standartlashtirilgan o‘lchovlar (chekka suyak darajasi, CBCT densitometriyasi, ISQ) bilan nazorat ostidagi tadqiqotlar tavsiya etiladi.</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>A‑PRF</kwd>
        <kwd>platelet concentrates</kwd>
        <kwd>immediate implantation</kwd>
        <kwd>radiography</kwd>
        <kwd>bone regeneration</kwd>
        <kwd>osseointegration</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>A‑PRF</kwd>
        <kwd>рентгенография</kwd>
        <kwd>имплантация</kwd>
        <kwd>остеоинтеграция</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>A‑PRF</kwd>
        <kwd>rentgenografiya</kwd>
        <kwd>implantatsiya</kwd>
        <kwd>suyak regeneratsiyasi</kwd>
      </kwd-group>
    </article-meta>
  </front>
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