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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i12.1924</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013235</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">YO‘G‘ON ICHAK ADENOKARSINOMASINI ENDOSKOPIK VA MORFOLOGIK DIAGNOSTIKA KORRELYASIYASI: O‘ZBEKISTONDAGI EPIDEMIOLOGIK TENDENSIYALAR VA SKRINING TEKSHIRUVI</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>THE CORRELATION OF ENDOSCOPIC AND MORPHOLOGICAL DIAGNOSIS OF COLON ADENOCARCINOMA: EPIDEMIOLOGICAL TRENDS AND SCREENING EXAMINATION IN UZBEKISTAN</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>КОРРЕЛЯЦИЯ ЭНДОСКОПИЧЕСКОЙ И МОРФОЛОГИЧЕСКОЙ ДИАГНОСТИКИ АДЕНОКАРЦИНОМЫ ТОЛСТОЙ КИШКИ: ЭПИДЕМИОЛОГИЧЕСКИЕ ТЕНДЕНЦИИ И СКРИНИНГОВОЕ ОБСЛЕДОВАНИЕ В УЗБЕКИСТАНЕ</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Gulmira Bazarbaeva Azimjonovna</string-name>
          <aff>Central Asian Medical University xalqaro tibbiyot universiteti</aff>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Sodiq Madaminov Madaminovich</string-name>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-01-05">
        <day>05</day>
        <month>01</month>
        <year>2026</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>12</issue>
      <fpage>171</fpage>
      <lpage>177</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013235/"/>
      <abstract xml:lang="uz">
        <p>Yo‘g‘on ichak adenokarsinomasi – kolorektal mintaqadagi eng ko‘p uchraydigan malign o‘sma bo‘lib, uning xalqaro va respublika darajasidagi epidemiologik tendensiyalari murakkab mexanizmlar asosida shakllanadi. Adenokarsinoma yuza epitelial hujayralarning giperplastik poliplardan boshlab, malign transformatsiyaga o‘tishi bilan rivojlanadi. Dunyo bo‘yicha kolorektal saraton holatlari yildan-yilga oshib borayotgani qayd etilgan, bu ozuqa odatlari, atrof-muhit omillari va hayot tarzi bilan chambarchas bog‘liq. Uzbekistan sharoitida ham kolorektal saraton incidence darajasi sezilarli bo‘lib, erkaklar va ayollarda 5.3 va 4.3 nafar/100,000 aholiga to‘g‘ri keladi. Endoskopik va morfologik diagnostika metodlari (masalan, kolonoskopiya va gistopatologik tahlil) ushbu patologiyani erta aniqlashda muhim ahamiyat kasb etadi. Ushbu maqola oid statistik va nazariy ma‘lumotlar asosida epidemiologik tendensiyalar, skriningning ahamiyati va diagnostika yo‘nalishlari ilmiylashtirilgan tarzda yoritiladi. Kalit so‘lar: yo‘g‘on ichak adenokarsinomasi, kolorektal saraton statistikasi, endoskopik diagnostika, morfologik tahlil, epidemiologiya, skrining modeli, adenokarsinoma patogenezisi, kolonoskopiya. КОЛОРЕКТАЛЬНАЯ АДЕНОКАРЦИНОМА: КОРРЕЛЯЦИЯ ЭНДОСКОПИЧЕСКОЙ И МОРФОЛОГИЧЕСКОЙ ДИАГ НОСТИКИ: ЭПИДЕМИОЛОГИЧЕСКИЕ ТЕНДЕНЦИИ И СКРИНИНГОВЫЕ ОБСЛЕДОВАНИЯ В УЗБЕКИСТАНЕ Гульмира Базарбаева Азимджонова Central Asian Medical University международного медицинского университета ассистент, ул-Бурхониддин Маргиниони, 64, Фергана, Узбекистан, E-mail: info@camuf.uz E-mail: ms.gulmir19831909@gmail.com Содик Мадаминов Мадаминович Кандидат медицинских наук, доцент Central Asian Medical University международного медицинского университета Центральной Азии, ул. Бурхониддин Маргиниони, 64, Фергана, Узбекистан, E-mail: info@camuf.uz</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>Colon adenocarcinoma is the most frequently encountered malignant tumour of the colorectal region, and its epidemiological trends at the international and national levels are shaped by complex mechanisms. Adenocarcinoma develops as the surface epithelial cells pass from hyperplastic polyps to malignant transformation. It has been recorded that cases of colorectal cancer are increasing worldwide from year to year, which is closely connected with dietary habits, environmental factors and lifestyle. In the conditions of Uzbekistan, too, the incidence of colorectal cancer is considerable, amounting to 5.3 and 4.3 per 100,000 population in men and women respectively. Endoscopic and morphological diagnostic methods (for example, colonoscopy and histopathological analysis) are of great importance in the early detection of this pathology. On the basis of the relevant statistical and theoretical data, this article sets out in a scientific manner the epidemiological trends, the importance of screening and the directions of diagnosis.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>Колоректальная аденокарцинома является наиболее часто встречающейся злокачественной опухолью в толстом кишечнике. Ее международные и национальные эпидемиологические тенденции формируются сложными механизмами. Аденокарцинома развивается от гиперпластических полипов эпителиальных клеток / слизистой оболочки до злокачественной трансформации. В мире регистрируется ежегодный рост случаев колоректального рака, что тесно связано с пищевыми привычками, факторами окружающей среды и образом жизни. В Узбекистане также отмечается значительный уровень заболеваемости колоректальным раком: 5,3 на 100 000 населения у мужчин и 4,3 на 100 000 населения у женщин. Эндоскопические и морфологические методы диагностики (например, колоноскопия и гистопатологическое исследование) имеют ключевое значение для раннего выявления патологии. В статье представлен ы статистические и теоретические данные по эпидемиологическим тенденциям, значению скрининга и направлениям диагностики.</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>yo‘g‘on ichak adenokarsinomasi</kwd>
        <kwd>kolorektal saraton statistikasi</kwd>
        <kwd>endoskopik diagnostika</kwd>
        <kwd>morfologik tahlil</kwd>
        <kwd>epidemiologiya</kwd>
        <kwd>skrining modeli</kwd>
        <kwd>adenokarsinoma patogenezisi</kwd>
        <kwd>kolonoskopiya</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>colon adenocarcinoma</kwd>
        <kwd>colorectal cancer statistics</kwd>
        <kwd>endoscopic diagnosis</kwd>
        <kwd>morphological analysis</kwd>
        <kwd>epidemiology</kwd>
        <kwd>screening model</kwd>
        <kwd>adenocarcinoma pathogenesis</kwd>
        <kwd>colonoscopy</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>аденокарцинома толстой кишки</kwd>
        <kwd>статистика колоректального рака</kwd>
        <kwd>эндоскопическая диагностика</kwd>
        <kwd>морфологический анализ</kwd>
        <kwd>эпидемиология</kwd>
        <kwd>модель скрининга</kwd>
        <kwd>патогенез аденокарциномы</kwd>
        <kwd>колоноскопия</kwd>
      </kwd-group>
    </article-meta>
  </front>
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