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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i11.1879</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013193</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>16.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">QON CHO‘PI (CHELIDONIUM MAJUS) O‘SIMLIGINING DORIVORLIK XUSUSIYATLARI VA CHISTOTEL PREPARATINING QUYONLAR TERISIGA FARMAKOTOKSIKOLOGIK TA‘SIRI</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>MEDICINAL PROPERTIES OF THE GREATER CELANDINE (CHELIDONIUM MAJUS) PLANT AND THE PHARMACOTOXICOLOGICAL EFFECT OF THE CHISTOTEL PREPARATION ON RABBIT SKIN</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>ЛЕКАРСТВЕННЫЕ СВОЙСТВА РАСТЕНИЯ ЧИСТОТЕЛ БОЛЬШОЙ (CHELIDONIUM MAJUS) И ФАРМАКОТОКСИКОЛОГИЧЕСКОЕ ДЕЙСТВИЕ ПРЕПАРАТА ЧИСТОТЕЛ НА КОЖУ КРОЛИКОВ</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>D.A.Ernazarov</string-name>
          <aff>Samarqand davlat veterinariya meditsinasi, chorvachilik va biotexnologiyalar universiteti Nukus filiali katta o‘qituvchisi, v.f.f.d (PhD)</aff>
        </contrib>
        <contrib contrib-type="author">
          <string-name>H.B.Niyozov</string-name>
          <aff>Samarqand davlat veterinariya meditsinasi, chorvachilik va biotexnologiyalar universiteti professori, v.f.d</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-12-05">
        <day>05</day>
        <month>12</month>
        <year>2025</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>11</issue>
      <fpage>354</fpage>
      <lpage>358</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013193/"/>
      <abstract xml:lang="uz">
        <p>Ushbu maqolada qon cho‘pi (Chelidonium majus.) o‘simligining kimyoviy tarkibi, biologik faol moddalari, uning asosida tayyorlanadigan chistotel preparatining farmakologik xususiyatlari hamda quyonlar terisiga bo‘lgan farmakotoksikologik ta‘siri o‘rganilgan. Tadqiqot natijalari o‘simlikdan olinadigan preparatlarning antimikrob, yallig‘lanishga qarshi va regeneratsiya jarayonini tezlashtiruvchi xususiyatlarini tasdiqlaydi.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>This article studies the chemical composition and biologically active substances of the greater celandine (Chelidonium majus.) plant, the pharmacological properties of the chistotel preparation produced on its basis, and its pharmacotoxicological effect on rabbit skin. The results of the research confirm the antimicrobial and anti-inflammatory properties of the preparations obtained from this plant and their ability to accelerate the process of regeneration.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>В статье изучены химический состав и биологически активные вещества растения чистотел большой (Chelidonium majus.), фармакологические свойства препарата чистотел, приготовленного на его основе, а также его фармакотоксикологическое действие на кожу кроликов. Результаты исследования подтверждают антимикробные, противовоспалительные и ускоряющие процесс регенерации свойства препаратов, получаемых из этого растения.</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>Qon cho‘pi</kwd>
        <kwd>сhelidonium majus</kwd>
        <kwd>chistotel</kwd>
        <kwd>quyonlar</kwd>
        <kwd>alkaloidlar</kwd>
        <kwd>farmakotoksikologiya</kwd>
        <kwd>teri regeneratsiyasi</kwd>
        <kwd>antimikrob ta‘siri</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>Greater celandine</kwd>
        <kwd>Chelidonium majus</kwd>
        <kwd>chistotel</kwd>
        <kwd>rabbits</kwd>
        <kwd>alkaloids</kwd>
        <kwd>pharmacotoxicology</kwd>
        <kwd>skin regeneration</kwd>
        <kwd>antimicrobial action</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>гвоздика</kwd>
        <kwd>Chelidonium majus</kwd>
        <kwd>чистотел</kwd>
        <kwd>кролики</kwd>
        <kwd>алкалоиды</kwd>
        <kwd>фармакотоксикология</kwd>
        <kwd>регенерация кожи</kwd>
        <kwd>антимикробное действие</kwd>
      </kwd-group>
    </article-meta>
  </front>
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</article>
