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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i11.1859</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-013175</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">COMPLICATIONS IN THE POSTOPERATIVE PERIOD IN PATIENTS WITH COMBINED TRAUMATIC BRAIN INJURY</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>ОСЛОЖНЕНИЯ В ПОСЛЕОПЕРАЦИОННОМ ПЕРИОДЕ У БОЛЬНЫХ С СОЧЕТАННОЙ ЧЕРЕПНО-МОЗГОВОЙ ТРАВМОЙ</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>QO‘SHMA BOSH MIYA JAROHATI BILAN OG‘RIGAN BEMORLARDA OPERATSIYADAN KEYINGI DAVRDAGI ASORATLAR</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Aliev Mansur Abdukholikovich</string-name>
          <aff>Specialized scientific and practical center for neurosurgery and neurorehabilitation at the Samarkand State Medical University</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-12-05">
        <day>05</day>
        <month>12</month>
        <year>2025</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>11</issue>
      <fpage>214</fpage>
      <lpage>225</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-013175/"/>
      <abstract xml:lang="en">
        <p>This study analyzes postoperative complications, mortality factors, and outcomes in 127 patients with severe combined traumatic brain injury (TBI) treated between 2020 and 2024. The research demonstrated that postoperative morbidity was largely determined by the severity of injury, patient age, preoperative neurological status, timing of surgery, and intraoperative management of cerebral edema. The overall postoperative mortality rate was 7.9%. Major predictors of death included brainstem lesions, massive brain edema with herniation, secondary hemorrhages, and delayed surgical intervention. Age-related comorbidities, such as hypertension, atherosclerosis, and pulmonary complications, contributed significantly to unfavorable outcomes in elderly patients. The study emphasizes that early surgical decompression, adequate anti-edema therapy, and comprehensive neurocritical care are essential for improving survival and functional recovery in patients with severe TBI.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>В работе представлен анализ послеоперационных осложнений, факторов летальности и исходов у 127 больных с тяжёлой сочетанной черепно-мозговой травмой (СЧМТ), лечившихся в 2020–2024 гг. Установлено, что исход заболевания во многом зависел от тяжести травмы, возраста пациентов, исходного неврологического статуса, сроков проведения операции и адекватности лечения отёка мозга. Общая послеоперационная летальность составила 7,9%. Основными причинами смерти явились поражения ствола мозга, массивный отёк с вклинением, вторичные кровоизлияния и задержка хирургического вмешательства. У пожилых пациентов исходы ухудшались из-за сопутствующих заболеваний — артериальной гипертензии, атеросклероза и лёгочных осложнений. Сделан вывод о необходимости ранней декомпрессивной операции, интенсивной противоотёчной терапии и мультидисциплинарного наблюдения для снижения летальности и улучшения неврологических исходов.</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>Ushbu tadqiqotda 2020–2024 yillar oralig‘ida og‘ir birlashgan bosh-miya jarohati (BBMJ) bilan davolangan 127 bemorning operatsiyadan keyingi asoratlari, o‘limga olib keluvchi omillar va natijalari tahlil qilindi. Tadqiqot natijalariga ko‘ra, operatsiyadan keyingi kechish ko‘p jihatdan jarohat og‘irligi, bemor yoshi, operatsiyagacha bo‘lgan nevrologik holati, jarrohlikning o‘z vaqtida bajarilishi hamda miya shishining intraoperatsion nazoratiga bog‘liq edi. Umumiy o‘lim darajasi 7,9% ni tashkil etdi. O‘limning asosiy sabablari — miya ustunining shikastlanishi, miya shishi va qisilishi, ikkilamchi qon quyilishlar hamda kechiktirilgan jarrohlik aralashuvi bo‘ldi. Keksalarda gipertoniya, ateroskleroz va o‘pka asoratlari kabi hamroh kasalliklar natijani yomonlashtirdi. Tadqiqot erta dekompressiv jarrohlik, intensiv shishga qarshi davolash va kompleks neyroreanimatsion kuzatuvning ahamiyatini tasdiqlaydi.</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>combined traumatic brain injury (TBI)</kwd>
        <kwd>brain edema</kwd>
        <kwd>brainstem hemorrhage</kwd>
        <kwd>postoperative complications</kwd>
        <kwd>mortality</kwd>
        <kwd>Glasgow Outcome Scale</kwd>
        <kwd>neurosurgery</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>сочетанная черепно-мозговая травма (ЧМТ)</kwd>
        <kwd>отёк головного мозга</kwd>
        <kwd>кровоизлияние в ствол мозга</kwd>
        <kwd>послеоперационные осложнения</kwd>
        <kwd>летальность</kwd>
        <kwd>шкала исходов Глазго</kwd>
        <kwd>нейрохирургия</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>birlashgan bosh-miya jarohati</kwd>
        <kwd>miya shishi</kwd>
        <kwd>miya ustuni qon ketishi</kwd>
        <kwd>operatsiyadan keyingi asoratlar</kwd>
        <kwd>o‘lim</kwd>
        <kwd>Glazgo natijalar shkalasi</kwd>
        <kwd>neyroxirurgiya</kwd>
      </kwd-group>
    </article-meta>
  </front>
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</article>
