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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.3" xml:lang="uz">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i5.1648</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-012974</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="uz">KLINIK ENDODONTIYADA IRRIGATSION ERITMALAR: TURLARI, XUSUSIYATLARI VA FAOLLASHTIRISH MEXANIZMLARI</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>IRRIGATION SOLUTIONS IN CLINICAL ENDODONTICS: TYPES, PROPERTIES AND ACTIVATION MECHANISMS</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="ru">
          <trans-title>ИРРИГАЦИОННЫЕ РАСТВОРЫ В КЛИНИЧЕСКОЙ ЭНДОДОНТИИ: ТИПЫ, СВОЙСТВА И МЕХАНИЗМЫ АКТИВАЦИИ</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Ergashev Bekzod Jaloliddin o‘g‘li</string-name>
          <aff>Central Asian Medical University xalqaro tibbiyot universiteti, Burhoniddin</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-06-05">
        <day>05</day>
        <month>06</month>
        <year>2025</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>5</issue>
      <fpage>215</fpage>
      <lpage>222</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>Ushbu asar Creative Commons Attribution 4.0 International litsenziyasi asosida litsenziyalangan.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-012974/"/>
      <abstract xml:lang="uz">
        <p>Ushbu adabiyotlar sharhida klinik endodontikada qo‘llaniladigan irrigatsiya eritmalarining turlari, xususiyatlari va faollashtirish mexanizmlari keng qamrovli tahlil qilingan. 58 ta dolzarb tadqiqot asosida sodium gipoxlorit keng spektrli antimikrobiyal va to‘qima eritish xususiyatlari tufayli asosiy irrigant sifatida e‘tirof etilgan. EDTA smear qatlamini olib tashlashda samarali ekani ko‘rsatilgan. MTAD va QMix kabi zamonaviy irrigantlarning ko‘p funksiyali xususiyatlari ta‘kidlangan bo‘lsa-da, ularning klinik natijalari hali to‘liq isbotlanmagan. Irrigantlarni faollashtirish irrigatsiya samaradorligini oshirishda hal qiluvchi ahamiyatga ega. Passiv ultrasonik irrigatsiya (PUI) irrigant penetratsiyasini oshirish va biofilmni yo‘qotishda eng samarali usul sifatida ajralib turadi. Sonik faollashtirish, salbiy bosim tizimlari va lazer yordamida irrigatsiya muqobil yoki yordamchi variantlar sifatida o‘rganilgan. Tahlil natijasida NaOCl va EDTA ni ultrasonik faollashtirish bilan birlashtirish optimal dezinfeksiya va uzoq muddatli klinik muvaffaqiyat uchun eng yaxshi natija berishini tasdiqlaydi. Xavfsizlik jihatlari, xususan irrigant ekstruziya va to‘qimalarga toksik ta‘siri, klinik protokol tanlashda hisobga olinishi lozim.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>This literature review provides a comprehensive analysis of the types, properties and activation mechanisms of the irrigation solutions used in clinical endodontics. On the basis of 58 current studies, sodium hypochlorite is recognised as the main irrigant owing to its broad-spectrum antimicrobial and tissue-dissolving properties. EDTA has been shown to be effective in removing the smear layer. Although the multifunctional properties of modern irrigants such as MTAD and QMix have been emphasised, their clinical results have not yet been fully proved. The activation of irrigants is of decisive importance in raising the effectiveness of irrigation. Passive ultrasonic irrigation (PUI) stands out as the most effective method for increasing irrigant penetration and eliminating biofilm. Sonic activation, negative pressure systems and laser-assisted irrigation have been studied as alternative or auxiliary options. The analysis confirms that combining NaOCl and EDTA with ultrasonic activation gives the best result for optimal disinfection and long-term clinical success. Safety considerations, in particular irrigant extrusion and the toxic effect on tissues, must be taken into account when selecting a clinical protocol.</p>
      </trans-abstract>
      <trans-abstract xml:lang="ru">
        <p>В данном обзоре литературы представлен всесторонний анализ типов, свойств и механизмов активации ирригационных растворов, используемых в клинической эндодонтии. На основании 58 современных исследований гипохлорит натрия признан основным ирригантом благодаря его широкому спектру антимикробных и растворяющих ткани свойств. Было показано, что ЭДТА эффективна в удалении смазанного слоя. Хотя многофункциональные свойства современных ирригантов, таких как MTAD и QMix, были подчеркнуты, их клинические результаты еще не полностью доказаны. Активация ирригаторов имеет решающее значение для повышения эффективности орошения. Пассивное ультразвуковое орошение (ПУИ) является наиболее эффективным методом повышения проникновения ирриганта и удаления биопленки. В качестве альтернативных или дополнительных вариантов рассматривались активация звуком, системы отрицательного давления и ирригация с помощью лазера. Анализ подтверждает, что сочетание NaOCl и ЭДТА с ультразвуковой активацией обеспечивает наилучшие результаты для оптимальной дезинфекции и долгосрочного клинического успеха. При выборе клинического протокола следует учитывать соображения безопасности, в частности, вытеснение ирригационного раствора и токсичность для тканей. /</p>
      </trans-abstract>
      <kwd-group xml:lang="uz">
        <kwd>Endodontiya</kwd>
        <kwd>Irrigatsiya</kwd>
        <kwd>Sodium gipoxlorit</kwd>
        <kwd>EDTA</kwd>
        <kwd>XlorGexidin</kwd>
        <kwd>Ultrasonik irrigatsiya</kwd>
        <kwd>Biofilm</kwd>
        <kwd>Ildiz kanali dezinfeksiyasi</kwd>
        <kwd>Lazer irrigatsiyasi</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <kwd>Endodontics</kwd>
        <kwd>Irrigation</kwd>
        <kwd>Sodium hypochlorite</kwd>
        <kwd>EDTA</kwd>
        <kwd>Chlorhexidine</kwd>
        <kwd>Ultrasonic irrigation</kwd>
        <kwd>Biofilm</kwd>
        <kwd>Root canal disinfection</kwd>
        <kwd>Laser irrigation</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>Эндодонтия</kwd>
        <kwd>Ирригация</kwd>
        <kwd>Гипохлорит натрия</kwd>
        <kwd>ЭДТА</kwd>
        <kwd>Хлоргексидин</kwd>
        <kwd>Ультразвуковая ирригация</kwd>
        <kwd>Биопленка</kwd>
        <kwd>Дезинфекция корневых каналов</kwd>
        <kwd>Лазерная ирригация</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
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</article>
