<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD with MathML3 v1.3 20210610//EN" "JATS-journalpublishing1-3-mathml3.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">research-focus</journal-id>
      <journal-title-group>
        <journal-title>Research Focus International Scientific Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">Research Focus</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub" publication-format="electronic">2181-3833</issn>
      <publisher>
        <publisher-name>Ilm-fan va innovatsiyalar akademiyasi</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.66073/researchfocus.v4i1.1273</article-id>
      <article-id pub-id-type="other" assigning-authority="relibrary.uz">REL-A-012760</article-id>
      <article-categories>
        <subj-group subj-group-type="oak">
          <subject>14.00.00</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">HEMOSTASIS SYSTEMS UNDER IMPACT THERMAL AGENT IN TOXEMIA FROM BURNS</article-title>
        <trans-title-group xml:lang="ru">
          <trans-title>СИСТЕМЫ ГЕМОСТАЗА ПОД ВОЗДЕЙСТВИЕМ ТЕРМИЧЕСКОГО АГЕНТА ПРИ ОЖОГОВОЙ ТОКСЕМИИ</trans-title>
        </trans-title-group>
        <trans-title-group xml:lang="uz">
          <trans-title>KUYISH TOKSEMIYASIDA TERMIK AGENT TA‘SIRI OSTIDA GEMOSTAZ TIZIMLARI</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author">
          <string-name>Yunusov O.T.</string-name>
          <aff>Samarkand State Medical University</aff>
        </contrib>
      </contrib-group>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-02-05">
        <day>05</day>
        <month>02</month>
        <year>2025</year>
      </pub-date>
      <pub-date date-type="collection">
        <year>2025</year>
      </pub-date>
      <volume>4</volume>
      <issue>1</issue>
      <fpage>171</fpage>
      <lpage>178</lpage>
      <permissions>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0">
          <ali:license_ref>https://creativecommons.org/licenses/by/4.0</ali:license_ref>
          <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="https://relibrary.uz/REL-A-012760/"/>
      <abstract xml:lang="en">
        <p>The evaluation of informative significance of homeostasis disturbance by degree of severity was carried out, and then the development of prognostic algorithms and verification of their effectiveness. It should be noted that all patients had deep burns from 10% to 45% of the body surface. Exactly these victims made up the basic array with the help of which the tasks on estimation of information significance and development of prognostic algorithm were solved. Adequate preoperative measures allowed to improve both the indices of the circulatory system and the clotting system in patients with mild and medium degree of plasmoporia.</p>
      </abstract>
      <trans-abstract xml:lang="ru">
        <p>Проведена оценка информативной значимости нарушений гомеостаза по степени выраженности, а затем разработка прогностических алгоритмов и проверка их эффективности. Следует отметить, что у всех пациентов были глубокие ожоги от 10% до 45% поверхности тела. Именно эти жертвы составили основной массив, с помощью которого решались задачи по оценке значимости информации и разработке прогностического алгоритма. Адекватные предоперационные мероприятия позволили улучшить как показатели системы кровообращения, так и системы свертывания крови у больных с легкой и средней степенью плазмопории.</p>
      </trans-abstract>
      <trans-abstract xml:lang="uz">
        <p>Gomeostaz buzilishlarining og‘irlik darajasi bo‘yicha informativ ahamiyati baholandi, so‘ngra prognostik algoritmlar ishlab chiqildi va ularning samaradorligi tekshirildi. Ta‘kidlash joizki, barcha bemorlarda tana yuzasining 10% dan 45% gacha bo‘lgan chuqur kuyishlari bo‘lgan. Aynan shu jabrlanuvchilar axborotning ahamiyatini baholash va prognostik algoritmni ishlab chiqish vazifalari hal etilgan asosiy massivni tashkil etdi. Adekvat operatsiyadan oldingi tadbirlar plazmoporiyaning yengil va o‘rta darajasidagi bemorlarda ham qon aylanish tizimi, ham qon ivish tizimi ko‘rsatkichlarini yaxshilash imkonini berdi.</p>
      </trans-abstract>
      <kwd-group xml:lang="en">
        <kwd>Disseminated Intravascular Clotting Syndrome</kwd>
        <kwd>Hemostasis</kwd>
        <kwd>Infusion Therapy</kwd>
        <kwd>Frank Index</kwd>
        <kwd>Plasma Therapy</kwd>
        <kwd>Necrectomy</kwd>
        <kwd>Burn Shock</kwd>
        <kwd>Hypercoagulation</kwd>
      </kwd-group>
      <kwd-group xml:lang="ru">
        <kwd>синдром диссеминированного внутрисосудистого свертывания крови</kwd>
        <kwd>гемостаз</kwd>
        <kwd>инфузионная терапия</kwd>
        <kwd>индекс Франка</kwd>
        <kwd>плазмотерапия</kwd>
        <kwd>некрэктомия</kwd>
        <kwd>ожоговый шок</kwd>
        <kwd>гиперкоагуляция</kwd>
      </kwd-group>
      <kwd-group xml:lang="uz">
        <kwd>Dissiminatsiyalangan qon tomir ichi ivish sindromi</kwd>
        <kwd>Gemostaz</kwd>
        <kwd>Infuzion terapiya</kwd>
        <kwd>Frank indeksi</kwd>
        <kwd>Plazmoterapiya</kwd>
        <kwd>Nekrektomiya</kwd>
        <kwd>Kuyish shoki</kwd>
        <kwd>Giperkoagulyatsiya</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <ref id="r1">
        <label>1</label>
        <mixed-citation>Baikulov A.K. Efficiency of chitosan derivatives on the process of skin regeneration at thermal burn (in Russian) // Actual issues of modern medical science and public health. - Yekaterinburg.- 2016.- T.3.- P.2567-2571.</mixed-citation>
      </ref>
      <ref id="r2">
        <label>2</label>
        <mixed-citation>Vazina I.R., Bougrov S.N., Sosin E.Yu. // Dynamics of lethality and cause of death for the last 40 years of the XX century in the Russian Burn Center of the Ministry of Health of the Russian Federation: scientific edition.// Vestnik Surgia.2004. №3. P-47-50.</mixed-citation>
      </ref>
      <ref id="r3">
        <label>3</label>
        <mixed-citation>Vazina I.R., Bougrov S.N., // Lethality and causes of death for the burned ones.// Russian Medical Journal. 2009. №3. P-14-17.</mixed-citation>
      </ref>
      <ref id="r4">
        <label>4</label>
        <mixed-citation>Vitkovskiy Yu.A., Podoynitsina V.I. Interleikiny 1 b, 1 c and the system of hemostasis at burned disease (in Russian) // Mat. of Intern. conf. &quot;Actual problems of thermal trauma&quot;. St. Petersburg (June 27-29), 2002. –P. 126-127.</mixed-citation>
      </ref>
      <ref id="r5">
        <label>5</label>
        <mixed-citation>Шеркулов, К. У., Шербеков, У. А., Рустамов, М. И., Сайдуллаев, З. Я., &amp; Узакбоева, М. Ж. (2017). Ожоги прямой кишки: диагностика и тактика лечения. in современные технологии: актуальные вопросы, достижения и инновации (pp. 87-90).</mixed-citation>
      </ref>
      <ref id="r6">
        <label>6</label>
        <mixed-citation>Раджабов, У. А., Шербеков, У. А., Рустамов, М. И., Шеркулов, К. У., &amp; Байсариев, Ш. У. (2017). Трансфузионное лечение ожоговой болезни препаратами и компонентами крови. In Молодежь и медицинская наука в XXI веке (pp. 377-378).</mixed-citation>
      </ref>
      <ref id="r7">
        <label>7</label>
        <mixed-citation>Voloshenko K.A., Berezenko E.A., Hakobyan S.R. Violation of hemostasis and correction in seriously burned // Emergency medical aid. Mat. of the interdepartmental conf. devoted to the 60th anniversary of the burn centre of the R.A. Lomonosov Scientific Research Institute of the emergency medicine (in Russian) // Emergency medical aid. I.I. Janelidze. St.-Petersburg (June, 20-22), 2006. - – №3. - T.7. - P. 49.</mixed-citation>
      </ref>
      <ref id="r8">
        <label>8</label>
        <mixed-citation>Karabayev B.H. Change of the blood coagulation system at burn shock in elderly people // Mat. of Intern. conf. &quot;Actual problems of thermal trauma&quot;. St. Petersburg (June 27-29), 2002. - P. 154-155.</mixed-citation>
      </ref>
      <ref id="r9">
        <label>9</label>
        <mixed-citation>Kovalenko O.N., Kozinets K.G. Violation of the clotting system in patients after early surgical treatment of burns // Moscow Interdepartmental Conf. &quot;Actual problems of the thermal trauma&quot;. St. Petersburg (June 27-29), 2002. - P. 163-164.</mixed-citation>
      </ref>
      <ref id="r10">
        <label>10</label>
        <mixed-citation>Юнусов, O., Карабаев, X., Тагаев, K., &amp; Рустамов, М. (2018). ДВС-синдром у обожженных: современный взгляд на проблему. Журнал проблемы биологии и медицины, (3 (102)), 109-113.</mixed-citation>
      </ref>
      <ref id="r11">
        <label>11</label>
        <mixed-citation>Даминов, Ф. А., Сайдуллаев, З. Я., &amp; Рустамов, И. М. (2023). Оперативное лечение ранних глубоких ожогов. Research Focus International Scientific Journal, 2(4), 238-241.</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
