research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v3i11.1191 REL-A-012682 14.00.00 CHRONIC KIDNEY DISEASE AND THE STATE OF THE CARDIOVASCULAR SYSTEM ХРОНИЧЕСКАЯ БОЛЕЗНЬ ПОЧЕК И СОСТОЯНИЕ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ SURUNKALI BUYRAK KASALLIGI VA YURAK-QON TOMIR TIZIMINING HOLATI Tairova Z.K. Samarkand State Medical University, Faculty of Dentistry, 1st year student; Scientific supervisor: Abulqosimova Dildora Asrorovna; Samarkand State Medical University, Department of Social and Humanitarian Sciences, assistant Xolbayev A.E. 05 12 2024 2024 3 11 244 247 https://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.

Chronic kidney disease (CKD) significantly increases the risk of cardiovascular complications and death. Patients with CKD frequently present with endothelial dysfunction, which plays an important role in the development of cardiovascular complications. This article discusses the development of cardiovascular risk, the consequences of endothelial dysfunction, as well as the importance of early diagnosis and treatment strategies.

Хроническая болезнь почек (ХБП) значительно увеличивает риск сердечно-сосудистых осложнений и смерти. У больных ХБП часто наблюдается эндотелиальная дисфункция, которая играет важную роль в развитии сердечно-сосудистых осложнений. В данной статье обсуждаются развитие сердечно-сосудистого риска, последствия эндотелиальной дисфункции, а также важность ранней диагностики и стратегии лечения.

Surunkali buyrak kasalligi (SBK) yurak-qon tomir asoratlari va o‘lim xavfini sezilarli darajada oshiradi. SBK bilan og‘rigan bemorlarda ko‘pincha endotelial disfunksiya kuzatiladi, u yurak-qon tomir asoratlari rivojlanishida muhim rol o‘ynaydi. Ushbu maqolada yurak-qon tomir xavfining shakllanishi, endotelial disfunksiya oqibatlari, shuningdek, erta tashxislashning ahamiyati va davolash strategiyalari muhokama qilinadi.

 chronic kidney disease cardiovascular risk endothelial dysfunction arterial hypertension atherosclerosis хроническая болезнь почек сердечно-сосудистый риск эндотелиальная дисфункция артериальная гипертензия surunkali buyrak kasalligi yurak-qon tomir xavfi endotelial disfunksiya arterial gipertenziya ateroskleroz Böhm, M., et al. (2020). "Endothelial Dysfunction in Chronic Kidney Disease." Journal of Hypertension, 38(2), 210-220. Daniel, B., et al. (2018). "The Association Between Endothelial Dysfunction and Cardiovascular Risk in CKD." Nephrology Dialysis Transplantation, 33(5), 926-935. Isakova, T., et al. (2011). "Phosphate and Mortality in Chronic Kidney Disease: A Clinical Perspective." Clinical Journal of the American Society of Nephrology, 6(4), 817-827. KDOQI Clinical Practice Guidelines for Nutrition in Chronic Kidney Disease (2012). American Journal of Kidney Diseases, 59(2), 27-48. Levey, A. S., Stevens, L. A., Schmid, C. H., et al. (2017). "A new equation to estimate glomerular filtration rate." Annals of Internal Medicine, 150(9), 604-612. Таирова З. К., Шодикулова Г. З. Шоназарова НХ REVMATOID ARTRIT BILAN KASALLANGAN BEMORLARDA KOMORBID KASALLIKLARNING UCHRASH CHASTOTASI //Журнал кардиореспираторных исследований. – 2022. – Т. 3. – №. 4. Sharma, K., et al. (2019). "Inflammation and Cardiovascular Disease in Chronic Kidney Disease." Cardiovascular Nephrology, 4(2), 57-65. Kamolidinovna T. Z., Zikriyaevna S. G. RISK FACTORS AND FEATURES OF CORONARY HEART DISEASE IN PATIENTS WITH RHEUMATOID ARTHRITIS //JOURNAL OF BIOMEDICINE AND PRACTICE. – 2022. – Т. 7. – №. 6. Mora-Fernández, C., Domínguez-Pimentel, V., De Fuentes, M. M., et al. (2014). "Cardiovascular Disease in Chronic Kidney Disease: The Role of Endothelial Dysfunction." Clinical Journal of the American Society of Nephrology, 9(4), 688-695.