research-focus Research Focus International Scientific Journal Research Focus 2181-3833 Ilm-fan va innovatsiyalar akademiyasi 10.66073/researchfocus.v2i10.538 REL-A-010749 STATE OF HUMORAL IMMUNITY IN PATIENTS WITH ATYPICAL PNEUMONIA IN FREQUENTLY ILL CHILDREN. СОСТОЯНИЕ ГУМОРАЛЬНОГО ИММУНИТЕТА У БОЛЬНЫХ С АТИПИЧНОЙ ПНЕВМОНИЕЙ У ЧАСТО БОЛЕЮЩИХ ДЕТЕЙ TEZ-TEZ KASALLANUVCHI BOLALARDA ATIPIK PNEVMONIYA BILAN OG‘RIGAN BEMORLARDA GUMORAL IMMUNITET HOLATI. Ibragimova Marina Fedorovna PhD, Acting Associate Professor, Department № 1 of Pediatrics and Neonatology Shavkatova Zilola Shobiddin kizi 2nd year master‘s resident at Department №1 of Pediatrics and Neonatology Samarkand State Medical University 05 11 2023 2023 2 10 125 128 https://creativecommons.org/licenses/by/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.

Atypical pneumonia remains one of the most common and severe diseases of the respiratory system in children [8]. Understanding the pathogenetic role of immune status can contribute to a deeper understanding of the mechanisms of disease development in atypical pneumonia, to develop effective strategies for diagnosing and treating the disease in frequently ill children. Questions regarding the study of the role of immune mechanisms in children with pneumonia and in the formation of a group of frequently ill children are quite controversial and insufficiently reflected, further study of which seems relevant. Currently, convincing data have been accumulated on the important role of the immune system in the formation and development of pneumonia in children

In our country, large-scale activities are being carried out for early diagnosis and prevention of somatic diseases among children, especially bronchopulmonary pathology.

Атипичные пневмонии остаются одной из распространённых и тяжело протекающих заболеваний дыхательной системы у детей [8]. Понимание патогенетической роли иммунного статуса могут способствовать более глубокому пониманию механизмов развития заболевания при атипичной пневмонии, для разработки эффективных стратегий диагностики и лечения заболевания у часто болеющих детей. вопросы по изучению роли иммунных механизмов у детей при пневмониях и в формировании группы часто болеющих детей достаточно противоречивы и отображены недостаточно, дальнейшее изучение которого представляются актуальным. В настоящее время накоплены убедительные данные о важной роли иммунной системы в формировании и развитии пневмонии у детей В нашей стране выполняются широкомасштабные мероприятия по ранней диагностике и профилактике соматических заболеваний среди детей, особенно бронхолёгочной патологии.

Atipik pnevmoniya bolalarda nafas olish tizimining eng ko‘p tarqalgan va og‘ir kechadigan kasalliklaridan biri bo‘lib qolmoqda [8]. Immun holatning patogenetik rolini tushunish atipik pnevmoniyada kasallik rivojlanish mexanizmlarini chuqurroq anglashga, tez-tez kasallanuvchi bolalarda kasallikni tashxislash va davolashning samarali strategiyalarini ishlab chiqishga xizmat qilishi mumkin. Bolalarda pnevmoniya vaqtida immun mexanizmlarning rolini va tez-tez kasallanuvchi bolalar guruhining shakllanishidagi o‘rnini o‘rganishga oid masalalar ancha ziddiyatli hamda yetarlicha yoritilmagan, ularni yanada o‘rganish dolzarb ko‘rinadi. Hozirgi vaqtda bolalarda pnevmoniyaning shakllanishi va rivojlanishida immun tizimning muhim roli haqida ishonchli ma‘lumotlar to‘plangan. Mamlakatimizda bolalar orasida somatik kasalliklarni, ayniqsa bronxo-o‘pka patologiyasini erta tashxislash va profilaktika qilish bo‘yicha keng ko‘lamli tadbirlar amalga oshirilmoqda.

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